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. 2022 Jan 12;29(1):1. doi: 10.5837/bjc.2022.001

Table 3. Summary of dosing reversal based on timing and size of last dose.

Factor Xa inhibitor

Last dose

Timing of last dose before andexanet alfa initiation

<8 hours or unknown

≥8 hours

Apixaban

≤5 mg

Low dose

Low dose

>5 mg/unknown

High dose

Rivaroxaban

≤10 mg

Low dose

Low dose

>10 mg/unknown

High dose