Table 3. Summary of dosing reversal based on timing and size of last dose.
Factor Xa inhibitor |
Last dose |
Timing of last dose before andexanet alfa initiation |
|
---|---|---|---|
<8 hours or unknown |
≥8 hours |
||
Apixaban |
≤5 mg |
Low dose |
Low dose |
>5 mg/unknown |
High dose |
||
Rivaroxaban |
≤10 mg |
Low dose |
Low dose |
>10 mg/unknown |
High dose |