Table 3.
Comparison of MRI morphological characteristics between IDH-mutant and IDH-wild type gliomas.
| Parameters | IDHmut (n = 48) | IDHwt (n = 112) | χ2 /Z value | P value | |
|---|---|---|---|---|---|
| Hemorrhage | Present | 8 (16.7%) | 22 (20.6%) | 0.322 | 0.570 |
| None | 40 (83.3%) | 85 (79.4%) | |||
| Cystic lesion | Present | 19 (39.6%) | 56 (52.3%) | 2.158 | 0.142 |
| None | 29 (60.4%) | 51 (47.7%) | |||
| Peritumoral edema | None | 12 (25.0%) | 29 (25.9%) | -7.767 | 0.443 |
| Mild | 16 (33.3%) | 25 (22.3%) | |||
| Severe | 20 (41.7%) | 58 (51.8%) | |||
| Tumor boundary | Clear | 21 (43.8%) | 50 (56.3%) | 0.011 | 0.917 |
| Blur | 27 (44.6%) | 62 (55.4%) | |||
| Enhancement pattern | No enhancement | 23 (48.9%) | 16 (14.4%) | 26.943 | < 0.001*** |
| Patchy enhancement | 16 (34.0%) | 34 (30.6%) | |||
| Rim enhancement | 8 (17.0%) | 61 (55.0%) | |||
| Distribution of lesions | Single lobe | 15 (31.3%) | 30 (26.8%) | 14.915 | 0.005** |
| Trans-lobe growth with corpus callosum involvement | 9 (18.8%) | 21 (18.8%) | |||
| Trans-lobe growth with insula involvement | 19 (39.6%) | 22 (17.9%) | |||
| Trans-lobe growth | 3 (6.3%) | 19 (17.0%) | |||
| Thalamus or brain stem | 2 (4.2%) | 22 (19.6) | |||
Significance level markers P < 0.01**, P < 0.001***.