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. 2022 May 27;10:890925. doi: 10.3389/fchem.2022.890925

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Copyright © 2022 Ma, Lu, Yang, Huang, Li and Ye.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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RuRe-1 and RuRe-2 induced the loss of MMP analyzed by confocal microscopy with Rh123 staining (λ _ex = 488 nm, λ _em = 530 ± 20 nm). The incubation time of the compounds was 6 h. Scale bar: 20 μm.