TABLE 1.
IC50 values of tested compounds towards different cell lines a .
| Compounds | IC50 (μM) | ||||
|---|---|---|---|---|---|
| HeLa | HepG2 | A549 | A549R | LO2 | |
| RuRe-1 | 3.1 ± 0.8 | 10.0 ± 0.8 | 11.8 ± 0.4 | 10.4 ± 1.2 | 25.1 ± 0.7 |
| RuRe-2 | 2.5 ± 1.3 | 12.5 ± 0.9 | 11.2 ± 0.9 | 16.7 ± 0.8 | 28.1 ± 1.1 |
| Ru-1 | 39.8 ± 0.6 | >50 | >50 | >50 | >50 |
| Ru-2 | 43.6 ± 1.2 | >50 | >50 | >50 | >50 |
| Re-1 | 7.7 ± 0.8 | 5.6 ± 0.5 | 6.9 ± 0.9 | 8.0 ± 1.1 | 5.8 ± 0.2 |
| Cisplatin | 19.3 ± 0.5 | 23.5 ± 2.0 | 25.9 ± 0.8 | 90.3 ± 0.3 | 22.5 ± 2.0 |
a
IC50 values are drug concentrations necessary for 50% inhibition of cell viability. The data are presented as mean ± standard deviation (SD) and cell viability is assessed after 48 h of incubation.