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. 2022 Jun 8;11(1):2085432. doi: 10.1080/2162402X.2022.2085432

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© 2022 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 7. — LAMs depletion in the TAME synergizes the antitumorigenic effects of anti-PD1 therapy.

(a) Balb/c mice inoculated with EMT6 cells were treated with anti-PD1 blocker and clophosome as scheduled. (b) The levels of CD163 are quantified by ImageJ after staining with the specific antibodies in paraffin-embedded tissues obtained from murine tumors. (c) Representative immunohistochemical images of CD163. (d-f) Growth curves (mean ± SEM), the representative images of tumors and tumor weight distributions at day 20 were shown.