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. 2022 May 27;13:889596. doi: 10.3389/fimmu.2022.889596

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Copyright © 2022 Hu, Lv, Huang, Yin, Gao, Liu, Yang, Zeng, Chen, Zhang, Zhang, Ma and Chen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Heatmap and volcano plot of the DEGs in different samples. The heatmap indicates that the expression patterns were significantly different in the eyes of BR14-induced animals (A) and IRBP-induced animals (B) compared to those of the control group. BR: Eyes in the BR14-induced group. IRBP: Eyes in the IRBP-induced group. C: Eyes in the healthy control group. (C) A volcano plot of the DEGs shows 401 upregulated genes (red dots) and 590 downregulated genes (blue dots) in the eyes of the BR14–induced group compared to the control group. (D) A volcano plot of the DEGs shows 520 upregulated genes (red dots) and 526 downregulated genes (blue dots) in the eyes of the IRBP-induced group compared to the control group.