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. 2022 May 27;13:860161. doi: 10.3389/fgene.2022.860161

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Copyright © 2022 Li, Chen, Luo, Wang, Yu, Gao and Zhong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of the molecular subtypes of OC patients using NMF. (A) The cophenetic, dispersion, evar, residuals, rss, silhouette, and sparseness distributions when rank k was set as 2 to 10. (B) Consensus map of NMF clustering for k = 2, which was the optimal cluster number in the TCGA-OV cohort. Kaplan-Meier (K-M) survival analyses were used to determine the OS (C) and PFS (D) prognosis of OC patients in two sub-consensuses classifications.