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. 2022 May 27;13:888961. doi: 10.3389/fphar.2022.888961

TABLE 2.

Summary of the antiviral activity of Viola tricolor peptide-enriched fractions.

Fraction # CC50 (µg/ml)* IC50 (µg/ml)* SI#
1 464.3 ± 31.9 >500 <0.9 ± 0.1
2 >500 >500 nd
3 485.8 ± 123.9 111.1 ± 114.2 8.3 ± 6.7
4 73.8 ± 32.5 21.0 ± 18.3 11.7 ± 15.5
5 103.2 ± 9.5 20.5 ± 28.2 18.6 ± 16.4

*CC50 and IC50 were determined by nonlinear regression from concentration-response curves (Figure 3). Values represent means ± SD of three independent experiments in triplicates. Since 500 μg/ml was the highest concentrations used, no higher half-maximal concentrations could be calculated.

#SI, was calculated by dividing CC50 by IC50. nd: not determined.