TABLE 2.
Fraction # | CC50 (µg/ml)* | IC50 (µg/ml)* | SI# |
---|---|---|---|
1 | 464.3 ± 31.9 | >500 | <0.9 ± 0.1 |
2 | >500 | >500 | nd |
3 | 485.8 ± 123.9 | 111.1 ± 114.2 | 8.3 ± 6.7 |
4 | 73.8 ± 32.5 | 21.0 ± 18.3 | 11.7 ± 15.5 |
5 | 103.2 ± 9.5 | 20.5 ± 28.2 | 18.6 ± 16.4 |
*CC50 and IC50 were determined by nonlinear regression from concentration-response curves (Figure 3). Values represent means ± SD of three independent experiments in triplicates. Since 500 μg/ml was the highest concentrations used, no higher half-maximal concentrations could be calculated.
#SI, was calculated by dividing CC50 by IC50. nd: not determined.