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. 2022 Jun 14;9(4):e1187. doi: 10.1212/NXI.0000000000001187

Figure 1. Study Design.

Figure 1

Second treatment course may be delayed for some patients, according to the lymphocyte count. *Highly active relapsing MS was defined as one relapse in the previous year and at least one T1 Gd+ lesion, or 9 or more T2 lesions while on therapy with other DMTs; or 2 or more relapses in the previous year whether on DMT or not. 9HPT = 9-hole peg test; CUA = combined unique active; EDSS = Expanded Disability Status Scale; KFS = Kurtzke Functional System; MS = multiple sclerosis; SDMT = Symbol Digit Modalities Test; T25FW = timed 25-foot walk; TB = tuberculosis.