TABLE 1.
ROB 2.0 assessment results of the included studies
| Study | Domain 1 | Domain 2 | Domain 3 | Domain 4 | Domain 5 | Overall |
|---|---|---|---|---|---|---|
| S128 | Some | Low | Low | Low | Some | Some |
| S241 | Some | High | High | Low | Some | High |
| S342 | Some | Some | Low | High | Some | High |
| S443 | Some | High | High | Low | Some | High |
| S544 | Some | Some | Low | Low | Some | Some |
| S645 | Some | Some | Low | Low | Some | Some |
| S746 | Low | Some | Low | Low | Some | Some |
| S847 | Some | Some | Low | Low | Some | Some |
| S948 | Some | Low | Low | Low | High | High |
| S1049 | Some | Some | Low | High | Some | High |
| S1150 | Some | Some | Low | Low | Some | Some |
| S1251 | Some | High | High | High | Some | High |
| S1352 | Some | High | High | High | Some | High |
| S1453 | Some | High | High | High | Some | High |
| S1554 | Low | High | High | High | Some | High |
| S1655 | Low | Some | Low | Low | Some | Some |
| S1756 | Some | Some | Low | Low | Some | Some |
| S1857 | Some | Some | Low | Low | Some | Some |
| S1958 | Some | Some | Low | Low | Some | Some |
| S2059 | Some | Some | Low | High | Some | High |
| S2160 | Some | Some | Low | High | Some | High |
| S2261 | Some | Some | Low | High | Some | High |
| S2362 | Low | Some | Low | Low | Some | Some |
| S2463 | Some | Some | Low | Low | Some | Some |
| S2564 | Some | Some | Low | Low | Some | Some |
| S2665 | Some | Some | Low | High | Some | High |
| S2766 | Some | Some | Low | Low | Some | Some |
| S2867 | Some | High | High | Low | Some | High |
| S2968 | Low | Some | Low | Low | Some | Some |
| S3069 | Some | Some | Low | High | Some | High |
| S3170 | Some | Low | Low | Low | Some | Some |
| S3271 | Some | Some | Low | Low | Some | Some |
| S3372 | Some | Some | Low | High | Some | High |
| S3473 | Some | Some | Low | High | Some | High |
| S3574 | Some | Some | Low | Low | Some | Some |
| S3675 | Some | Some | Low | High | Some | High |
| S3776 | Some | Some | Low | High | Some | High |
| S3877 | Some | Some | Low | High | Some | High |
| S3978 | Some | Some | Low | High | Some | High |
| S4079 | Some | Some | Low | Some | Some | Some |
| S4180 | Low | Some | Low | Some | Some | Some |
| S4281 | Some | Some | Low | High | Some | High |
Domain 1, risk of bias arising from the randomization process; domain 2, risk of bias due to deviations from the intended interventions (effect of assignment to intervention); domain 3, risk of bias due to missing outcome data; domain 4, risk of bias in measurement of the outcome; domain 5, risk of bias in selection of the reported result; high, high risk of basis; low, low risk of basis; ROB 2.0, version 2 of the Cochrane risk-of-bias tool; S, study; some, some concerns.