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. 2022 May 30;12:882292. doi: 10.3389/fonc.2022.882292

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Copyright © 2022 Bao, Li, Guan, Yao, Liang, Xiang and Zhong

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differences of biological features and immune profiles of three m1A clusters in LUAD. (A–C) GSVA results revealed specific biological pathways of three m1A modification patterns. (A) Cluster A vs. cluster B; (B) cluster A vs. cluster C; (C) cluster B vs. cluster C. (D–G) Violin plots depicted the distribution of ESTIMATE, immune, and stroma scores as well as tumor purity in three m1A modification patterns. (H) Differences in abundance of 23 TME-infiltrating cells under three m1A modification patterns. ** indicates p < 0.01; *** indicates p < 0.001.