TABLE 2.
Total fat mass (kg) | Trunk fat mass (kg) | Android fat mass (kg) | Gynoid fat mass (kg) | Right leg fat mass (kg) | Gluteofemoral fat mass (kg) | Android‐to‐gynoid ratio | Subcutaneous adipose tissue area (cm2) | Muscle compartment adipose tissue area (cm2) | Mean muscle density (HU) | |||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
B | 95% | CI | B | 95% | CI | B | 95% | CI | B | 95% | CI | B | 95% | CI | B | 95% | CI | B | 95% | CI | B | 95% | CI | B | 95% | CI | B | 95% | CI | |
Univariable model | ||||||||||||||||||||||||||||||
Time | 0.69 *** | 0.57 | 0.81 | 0.46 *** | 0.38 | 0.55 | 0.09 *** | 0.07 | 0.11 | 0.08 *** | 0.05 | 0.10 | 0.07 *** | 0.05 | 0.09 | 0.27 *** | 0.22 | 0.32 | 0.01 *** | 0.01 | 0.01 | 1.24 *** | 0.77 | 1.72 | 0.15 | −0.11 | 0.30 | −0.46 ** | −0.76 | −0.17 |
Multivariable model a | ||||||||||||||||||||||||||||||
Time | 0.68 *** | 0.55 | 0.80 | 0.45 *** | 0.37 | 0.54 | 0.09 *** | 0.07 | 0.11 | 0.07 *** | 0.05 | 0.09 | 0.07 *** | 0.04 | 0.09 | 0.27 *** | 0.21 | 0.32 | 0.01 *** | 0.01 | 0.01 | 1.05 *** | 0.49 | 1.60 | −0.14 | −0.03 | 0.32 | −0.23 | −0.58 | 0.12 |
Hormone use | ||||||||||||||||||||||||||||||
E+P4 | −4×10−3 | −0.75 | 0.74 | −0.07 | −0.59 | 0.45 | −0.05 | −0.16 | 0.05 | 0.08 | −0.05 | 0.22 | 2×10−3 | −0.15 | 0.15 | −0.07 | −0.39 | 0.24 | −0.01 | −0.03 | 2×10−3 | −0.08 | −2.37 | 2.22 | −7×10−3 | −0.80 | 0.78 | −0.86 | −2.33 | 0.62 |
E | −0.12 | −2.34 | 2.09 | 0.02 | −1.51 | 1.55 | −0.03 | −0.34 | 0.27 | −0.12 | −0.52 | 0.29 | −0.06 | −0.49 | 0.36 | −0.17 | −1.10 | 0.76 | 0.01 | −0.03 | 0.05 | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ |
P4 | −0.19 | −0.90 | 0.52 | −0.24 | −0.72 | 0.24 | −0.02 | −0.12 | 0.07 | −0.01 | −0.14 | 0.12 | −0.06 | −0.20 | 0.08 | −0.18 | −0.47 | 0.12 | 1×10−4 | −0.01 | 0.01 | 0.37 | −6.15 | 6.90 | 0.15 | −2.17 | 2.47 | −1.02 | −5.61 | 3.58 |
DQS | −0.23 ** | −0.37 | −0.09 | −0.16 ** | −0.26 | −0.07 | −0.02 ** | −0.04 | −0.01 | −0.04 ** | −0.06 | −0.01 | −0.03 * | −0.06 | −0.01 | −0.08 ** | −0.14 | −0.02 | −1×10−3 | −4×10−3 | 1×10−3 | −0.19 | −0.66 | 0.27 | −2×10−3 | −0.15 | 0.15 | 0.05 | −0.20 | 0.30 |
SR‐PA | −0.17 *** | −0.25 | −0.08 | −0.11 *** | −0.17 | −0.06 | −0.02 *** | −0.03 | −0.01 | −0.03 *** | −0.04 | −0.01 | −0.03 ** | −0.04 | −0.01 | −0.07 *** | −0.10 | −0.03 | −3×10−3** | −4×10−3 | −1×10−3 | −0.37 * | −0.69 | −0.04 | −0.05 | −0.16 | 0.06 | 0.25 * | 0.04 | 0.46 |
Time x SR‐PA | −3×10−4 | −0.04 | 0.04 | 4×10−4 | −0.02 | 0.02 | 1×10−3 | −4×10−3 | 0.01 | 3×10−3 | −3×10−3 | 0.01 | 2×10−3 | −5×10−3 | 0.01 | −2×10−3 | −0.02 | 0.01 | 3×10−4 | −3×10−4 | 1×10−3 | −0.18 | −0.37 | 0.02 | 3×10−3 | −0.06 | 0.07 | 0.10 | −0.03 | 0.22 |
Abbreviations: DXA, dual‐energy X‐ray absorptiometry; CT, computed tomography; SR‐PA, centered self‐reported physical activity in MET‐hours/day; Note: DXA, dual‐energy X‐ray absorptiometry; CT, computed tomography; SR‐PA, centered self‐reported physical activity in MET‐hours/day; MET, metabolic equivalent of a task; HU, Hounsfield unit; B, unstandardized regression coefficient; CI, confidence interval; Time: follow‐up time in years; Hormone use: reference group is non‐hormone users; E, estrogen; P4, progestogen; DQS: centered diet quality score.
Model adjusted with centered baseline age and education level. Significant (p < 0.05) B values in bold.
p < 0.001
p < 0.01
p < 0.05.