Table 1.
Summary of the demographic and clinical characteristics of all participants.
| Items | MMD (n = 16) | AS-ICASO (n = 5) | p |
|---|---|---|---|
| Age (mean ± SD) | 54.94 ± 5.53 | 59.60 ± 10.64 | 0.204 |
| Sex (male/female) | 8/8 | 3/2 | 0.999 |
| Family history of MMD | 0 | 0 | 0.999 |
| Initial symptom | |||
| ICH | 4 | 0 | 0.532 |
| IVH | 2 | 0 | 0.999 |
| SAH | 1 | 0 | 0.999 |
| CI | 7 | 4 | 0.311 |
| TIA | 2 | 1 | 0.999 |
| Subtotal (hemorrhage/ | 7/9 | 0/5 | 0.123 |
| ischemia) | |||
| Medical history | |||
| Hypertension | 4 | 4* | 0.047 |
| Diabetes mellitus | 2 | 2 | 0.228 |
| Hyperlipidemia | 0 | 1 | 0.238 |
| Subtotal | 6 | 5 | 0.035 |
| Mutation in RNF213 | 0 | 0 | 0.999 |
Values represent the number of patients unless indicated otherwise. Statistical analyses were performed using an unpaired student's t-test for continuous variables and the Fisher's exact test for categorical variables. ICH, intracerebral hemorrhage; IVH, intraventricular hemorrhage; SAH, subarachnoid hemorrhage; TIA, transient ischemic attack; CI, cerebral infarction.
*
In the atherosclerosis-associated intracranial artery stenosis/occlusion (AS-ICASO) group, two subjects have both hypertension and diabetes mellitus.