Table 2.
Top 10 upregulated or downregulated sex-specific differentially expressed genes (DEGs) in middle cerebral artery (MCA) samples in men patients with Moyamoya disease (MMD).
| Gene symbol | Ensemble ID | Fold change | p |
|---|---|---|---|
| Upregulated genes | |||
| AQP4 | ENSG00000171885 | 5.2 | 5.8E-05 |
| FUT9 | ENSG00000172461 | 4.7 | 3.8E-04 |
| KCNH7 | ENSG00000184611 | 4.5 | 2.0E-05 |
| CADM2 | ENSG00000175161 | 3.9 | 2.0E-04 |
| LSAMP | ENSG00000185565 | 3.8 | 1.5E-05 |
| PPM1E | ENSG00000175175 | 3.5 | 7.0E-05 |
| NEFL | ENSG00000277586 | 3.5 | 2.1E-03 |
| KIF14 | ENSG00000118193 | 3.4 | 1.0E-04 |
| LOC105379109 | ENSG00000251574 | 3.1 | 1.1E-04 |
| CENPE | ENSG00000138778 | 2.9 | 1.0E-05 |
| Downregulated genes | |||
| ATP1A2 | ENSG00000018625 | 6.4 | 7.0E-07 |
| F3 | ENSG00000117525 | 6.2 | 2.5E-08 |
| LGI4 | ENSG00000153902 | 4.3 | 1.6E-07 |
| METTL7A | ENSG00000185432 | 4.1 | 6.0E-05 |
| DST | ENSG00000151914 | 3.6 | 1.5E-05 |
| CPE | ENSG00000109472 | 3.5 | 1.4E-02 |
| SRRM2 | ENSG00000167978 | 3.5 | 1.0E-03 |
| NARS1 | ENSG00000134440 | 3.4 | 1.7E-05 |
| CCDC124 | ENSG00000007080 | 3.3 | 3.3E-04 |
| RAD23A | ENSG00000179262 | 3.3 | 4.5E-04 |