Table 3.
Top 10 upregulated or downregulated sex-specific DEGs in MCA samples in women patients with MMD.
| Gene symbol | Ensemble ID | Fold change | p |
|---|---|---|---|
| Upregulated genes | |||
| SOD3 | ENSG00000109610 | 18.0 | 1.03E-13 |
| NR4A1 | ENSG00000123358 | 15.9 | 8.16E-10 |
| PPDPF | ENSG00000125534 | 14.7 | 5.57E-15 |
| AEBP1 | ENSG00000106624 | 13.2 | 3.02E-12 |
| MYADM | ENSG00000179820 | 12.6 | 3.97E-13 |
| PNRC1 | ENSG00000146278 | 12.6 | 3.87E-12 |
| AHNAK | ENSG00000124942 | 12.5 | 1.99E-08 |
| COL1A2 | ENSG00000164692 | 12.2 | 5.75E-15 |
| IER2 | ENSG00000160888 | 12.0 | 1.44E-11 |
| IGFBP5 | ENSG00000115461 | 11.8 | 1.30E-10 |
| Downregulated genes | |||
| CTNND2 | ENSG00000169862 | 3.2 | 1.0E-03 |
| CAMK2N1 | ENSG00000162545 | 3.0 | 2.5E-02 |
| KIF5A | ENSG00000155980 | 3.0 | 3.1E-06 |
| NRXN1 | ENSG00000179915 | 2.9 | 6.8E-05 |
| OLFM1 | ENSG00000130558 | 2.9 | 1.6E-03 |
| CAMK2A | ENSG00000070808 | 2.7 | 1.3E-03 |
| CNKSR2 | ENSG00000149970 | 2.5 | 6.1E-05 |
| SCN8A | ENSG00000196876 | 2.5 | 9.1E-06 |
| CAMK2B | ENSG00000058404 | 2.5 | 5.6E-03 |
| SRGAP3 | ENSG00000196220 | 2.3 | 1.1E-04 |