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. Author manuscript; available in PMC: 2022 Nov 26.
Published in final edited form as: Nat Microbiol. 2022 May 26;7(6):918–927. doi: 10.1038/s41564-022-01128-6

Extended Data Fig. 6. Code change machinery in two TGA-recoded Jade phages.

Extended Data Fig. 6

A. An operon implicated in changing the genetic code from standard code (TGA = Stop) to code 4 (TGA = W) is directly upstream of the lysis cassette. The code change genes themselves are encoded in standard code, while some genes in the lysis cassette have in frame TGA codons (green). TrpRS = Tryptophanyl tRNA synthetase, RF1 = Release Factor 1, TM-domain = Transmembrane domain.