Figure 3.
Biplot showing the factor loadings by the individual cytokines and acute phase proteins on the first two principal components (PC1 and PC2), and the values of these components for each individual in the study [n = 747, Groups: 0 = unaffected controls (red circles); 1 = ASD-cases (blue triangles)], in the two-dimensional component space generated by PC1 and PC2. A2M, α-2 Macroglobulin; APP, Acute Phase Protein; CRP, C-Reactive Protein; Cyto, Cytokine; FER, Ferritin; FIB, Fibrinogen; IL-1β, Interleukin-1β; IL-2, Interleukin-2; IL-4, Interleukin-4; IL-5, Interleukin-5; IL-6, Interleukin-6; IL-7, Interleukin-7; IL-8, Interleukin-8; IL-10, Interleukin-10; IL-12, Interleukin-12; IL-13, Interleukin-13; IL-17, Interleukin-17; GCSF, Granulocyte Colony-Stimulating Factor; GMCSF, Granulocyte Monocyte Colony-Stimulating Factor; IFN-γ, Interferon-γ MCP-1, Monocyte Chemoattractant Protein 1; MIP-1β, Macrophage Inflammatory Protein 1β; PCT, Procalcitonin; SAA, Serum Amyloid A; Serum Amyloid P; tPA, Tissue Plasminogen Activator; TNF-α, Tumor Necrosis Factor-α.