Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 May 31;13:876602. doi: 10.3389/fendo.2022.876602

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Cristalli, Manara, Valente, Pellegrini, Bavelloni, De Feo, Blalock, Di Bello, Piñeyro, Merkel, Esteller, Tirado, Mai and Scotlandi

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

MC3343 and 5azadC kinetics of DNA damage induction. (A) Merged immunofluorescence of TC-71 and A-673 staining for γH2AX (green) and DAPI (blue) after 3, 6 and 24h of treatment with DMSO, MC3343 or 5azadC. Digital images were acquired under identical conditions at the same time, using image analysis software (NIS Elements, Nikon). Representative images are shown. Scale bars, 20 µm. (B) DNA DSBs measured by levels of mean fluorescence intensity (MFI) of γH2AX positive nuclei in at least 20 different fields for each condition. (*p < 0.05; ***p < 0.001, one-way ANOVA test).