表 2.
多元变量统计分析sham组与CLP组小鼠MDSCs中氨基酸及寡肽含量
Multivariate statistical analysis of amino acid and oligopeptide contents in MDSCs of mice in sham and CLP groups /(μmol/L)
| Amino acids | Sham group (n=5) | CLP group (n=5) | VIP | Corr.Coeffs. |
| Normally distributed data are expressed as mean ± standard deviation, and non-normally distributed data are expressed as median [quartile]. CLP, cecal ligation and puncture; MDSCs, myeloid-derived suppressor cells; VIP, variable importance in projection; Corr.Coeffs, correlation coefficient. | ||||
| Leucine | 219.580±34.095 | 587.560±79.165 | 1.144 | 0.977 |
| Threonine | 112.160±5.280 | 269.220±40.306 | 1.142 | 0.976 |
| Glycine | 386.660±77.645 | 995.180±65.567 | 1.135 | 0.970 |
| Serine | 444.380±60.045 | 1251.500±187.629 | 1.129 | 0.964 |
| Phenylalanine | 116.560±11.250 | 301.400±51.594 | 1.124 | 0.960 |
| Tyrosine | 89.080±14.074 | 243.940±47.185 | 1.121 | 0.957 |
| Aspartic acid | 122.680±44.956 | 555.440±118.618 | 1.117 | 0.954 |
| Glutamate | 522.220±186.936 | 2 490.800 (1 678.900, 2 631.900) | 1.107 | 0.945 |
| Methionine | 62.860±20.195 | 127.240±6.354 | 1.107 | 0.946 |
| Lysine | 224.020±47.647 | 666.820±134.086 | 1.107 | 0.946 |
| 4-hydroxyproline | 217.480±54.856 | 729.100±189.424 | 1.087 | 0.928 |
| Histidine | 98.200±16.996 | 202.380±36.155 | 1.076 | 0.919 |
| Tryptophan | 24.700±9.100 | 103.200±30.850 | 1.075 | 0.918 |
| Valine | 195.400±45.947 | 548.020±136.323 | 1.074 | 0.918 |
| Alanine | 921.900 (870.000, 948.200) | 3 029.320±780.214 | 1.024 | 0.874 |
| Proline | 96.800 (95.400, 104.800) | 375.700±121.282 | 1.021 | 0.872 |
| Asparagine | 64.500±28.406 | 140.580±23.324 | 1.009 | 0.862 |
| Aminoadipic acid | 14.500 (13.800, 14.900) | 42.380±13.225 | 0.997 | 0.852 |
| Citrulline | 49.140±18.249 | 124.040±39.186 | 0.982 | 0.838 |
| Glutamine | 297.100 (277.400, 300.600) | 1 452.940±559.859 | 0.967 | 0.826 |
| Taurine | 4 646.620±2 425.105 | 8 336.720±739.823 | 0.961 | 0.821 |
| α-aminobutyric acid | 27.740±14.200 | 83.200±34.351 | 0.945 | 0.807 |
| 5-hydroxylysine | 2.516±2.567 | 15.620±8.233 | 0.925 | 0.790 |
| Ornithine | 91.960±58.453 | 312.800±160.012 | 0.888 | 0.758 |
| Arginine | 137.380±68.239 | 305.500±105.690 | 0.863 | 0.737 |
| Cystine | 0.180±0.000 | 12.376±12.628 | 0.775 | 0.662 |
| Kynurenine | 8.520±1.359 | 10.340±1.383 | 0.704 | 0.601 |
| Carnosine | 20.138±15.920 | 40.700±24.508 | 0.540 | 0.461 |
| Glutathione | 273.980±94.760 | 189.800 (187.300, 268.800) | 0.362 | -0.310 |