Table 2.

Taxa Associated with Cancer and Cancer Treatment-related Symptoms

Outcomes or Toxicities	Key Taxa
Patients with cancer (vs healthy controls)	Decrease in Firmicutes, Actinobacteria, Bacteroides, Bifidobacteria, Clostridium cluster IV and XIVa, Faecalibacterium, Lactobacillus, Faecalibacterium, Lachnospiracea, Oscillibacter, and Roseburia Increase in Proteobacteria, Enterobacteriaceae, Enterococci, Fusobacteria, Gammaproteobacteria, Streptococcus, Dorea, Subdoligranulum, and Escherichia-Shigella
High gastrointestinal symptoms (vs low gastrointestinal symptoms)	Decrease in Actinobacteria, Lactobacillus, Faecalibacterium, Roseburia, and Bifidobacterium Increase in Escherichia coli, Enterobacter, Staphylococcus, Phascolarctobacterium, Lachnospiraceae, Erysipelotrichaceae, Clostridium XI and XVIII, and Fecalitalea
High psychoneurological symptoms (vs low psychoneurological symptoms)	Decrease in Firmicutes, Ruminiclostridium, Phascolarctobacterium, and Subdoligranulum Increase in Bacteroidetes, Anaerofustis, Tyzzerella, Intestinimonas, and Family XIII AD3011
Low psychoneurological symptoms (vs high psychoneurological symptoms)	Increase in Lactococcus, Lactobacillus, Phascolarctobacterium, Acidaminococcaceae, Desulfovibrio, Bacteroides, Blautia1, Ruminococcaceae, and Oscillibacter