Fig. 3.

Perivascular (A) and scar-associated (B) macrophages in the myocardium of hypertensive db/db mice. Db/db mice were treated with angiotensin II for 4 weeks via infusion from subcutaneously implanted minipumps. The hearts were harvested at the age of 21 weeks, frozen, and immunostained as indicated on panels. Analysis was performed under a confocal microscope (Leica, Wetzlar, Germany). WGA, wheat germ agglutinin demarcates cell borders. Scale bar, 50 μm