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. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: Transplant Cell Ther. 2022 Mar 15;28(6):325.e1–325.e7. doi: 10.1016/j.jtct.2022.03.014

Table 1.

Demonstration of reproducible results

Published Results
Overall survival Events/Evaluable Hazard Ratio (95% confidence interval) p-value
Age
≤12 years 22/491 1.00
13 – 49 years 54/419 3.15 (1.86 – 5.34) <0.0001
Regimen intensity
Non-myeloablative 7/181 1.00
Myeloablative 41/478 4.62 (1.87 – 11.44) 0.0009
Reduced intensity 28/251 3.79 (1.46 – 9.84) 0.006
Donor type
HLA-matched sibling 21/558 1.00
Haploidentical relative 13/137 2.94 (1.26 – 6.87) 0.013
HLA-matched unrelated 26/111 5.12 (2.79 – 9.40) <0.0001
HLA-mismatched unrelated 16/104 4.88 (2.22 – 10.75) <0.0001
Results from Public Database with Additional Follow up for Published Cohort
Overall survival Events/Evaluable Hazard Ratio (95% confidence interval) p-value
Age
≤12 years 23/491 1.00
13 – 49 years 59/419 3.50 (2.16 – 5.79) <0.0001
Regimen intensity
Non-myeloablative 9/181 1.00
Myeloablative 44/478 3.59 (1.57 – 8.21) 0.002
Reduced intensity 29/251 3.08 (1.29 – 7.39) 0.012
Donor type
HLA-matched sibling 25/558 1.00
Haploidentical relative 13/137 2.70 (1.29 – 5.67) 0.009
HLA-matched unrelated 27/111 4.36 (2.47 – 7.70) <0.0001
HLA-mismatched unrelated 17/104 3.55 (1.90 – 6.65) <0.0001