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. 2022 Jun 14;13:3428. doi: 10.1038/s41467-022-30678-w

Fig. 2. Comparison of the number of significant loci identified by PheWAS and MultiPhen from eMERGE and UK Biobank.

Fig. 2

The p-value threshold is 1 × 10−4. The number of loci are counted when they suggest significant associations with at least one phenotype. For PheWAS, we included the SNPs when its minimum p-value among phenotypes passed the threshold. Here, the total number of loci represents the independent loci we tested in both eMERGE and the UK Biobank.