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Time course of systolic arterial pressure from 3 weeks (prehypertensive phase) until 27 weeks of age in four groups of female rats: untreated SHR (n = 8, filled black circle), OPC 21268-treated SHR (n = 10, open red circle), OPC 41061-treated SHR (n = 10, open blue circle), and untreated WKY (n = 12, open yellow circle). Green rectangle indicates the active period of drug treatment (24 days). Data are expressed as means ± SD. *p < 0.01.
