FIGURE 3.

Exosome uptake by neighbouring cells: Schematic representation of exosome uptake by neighbouring cells. Once secreted into the extracellular space, exosomes can be taken up by neighbouring cells via two main processes i) exosomes are engulphed into the target cell via endocytosis. Once endocytosed exosomes fuse with the endocytic compartment delivering various cargo ii) exosomes dock onto the plasma membrane of the target cell and directly deliver their cargo into the cytoplasm of the target cell.