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. 2022 Jun 1;10:886642. doi: 10.3389/fcell.2022.886642

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Copyright © 2022 Gupta, Malkin and Huang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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A schematic representation of the process of tRNA biogenesis. tRNA biogenesis begins with transcription of tRNA to form pre-tRNA. This pre-tRNA is then processed to form a mature tRNA before being exported from the nucleus. The mature tRNA is then ready to be charged with an amino acid by an aminoacyltRNA synthetase.