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. 2022 Jun 1;10:876803. doi: 10.3389/fped.2022.876803

Table 2.

Participant characteristics (N = 43).

MOS-R <25
(n = 24)
MOS-R 25–28,
(n = 19)
P -value
Gestational age (weeks) 27.6 ±1.52 27.5 ±1.50 0.85T
Birth weight (g) 1,023.2 ±216.4 986.6 ±279.1 0.63T
Small for gestational age 3 (12.5) 2 (10.5) 0.84F
Male sex 14 (58.3) 8 (42.1) 0.36F
Multiple pregnancy 2 (8.3) 4 (21.1) 0.38F
C-section delivery 10 (41.7) 12 (63.2) 0.86X
Prenatal steroids 15 (62.5) 15 (78.9) 0.24X
Apgar score 8 (7–8) 8 (7–9) 0.34U
NICU stay (days) 15.0 (5.0–29.0) 16.5 (8.3–23.8) 0.57U
Postnatal steroids 5 (20.8) 3 (15.7) 1.00F
Mechanical ventilation (days) 6 (1–11) 2 (1–19) 0.83U
NEC 3 (12.5) 5 (26.3) 0.43F
Sepsis 7 (29.2) 3 (15.7) 0.47F
PDA 12 (50.0) 10 (52.6) 1.00F
Genes present
EPO 20 (83.3) 18 (94.7) 0.36F
SLC6A3 19 (79.2) 18 (94.7) 0.21F
TLR4 20 (83.3) 16 (84.2) 1.00F
VEGFA 23 (94.8) 16 (84.2) 0.31F
LEP 20 (83.3) 16 (84.2) 1.00F
NR3C1 18 (75.0) 17 (89.5) 0.27F
HSD11B2 14 (48.3) 12 (63.2) 0.75F

Characteristics given as mean ± SD, median (P25–P75), n (%) according to their distribution.

MOS-R, Motor Optimality Score-Revised; NICU, Neonatal Intensive Care Unit; NEC, Necrotizing Enterocolitis defined as Bell stage >2A; PDA, Persistent Ductus Arteriosus treated with ibuprofen or clip. Sepsis was blood culture proven. Small for gestational age was defined as a birth weight below the 10th percentile on Dutch growth charts.

U

Mann–Whitney U-Test,

T

Students T-test,

X

Chi-square Test,

F

Fisher's Exact Test.