TABLE 1.

Exosome gDNA as biomarkers for diagnosis of diseases.

Disease	Mutantion	Detection mode	Biofluid	Reference
Pancreatic Cancer	KRAS TP53	ddPCR	Plasma	(Kahlert et al., 2014; Yang et al., 2017)
Glioma	EGFR	Conventional PCR	Cerebrospinal fluid	Vaidya and Sugaya, (2020)
non-small cell lung cancer	EGFR	PNA-PCR	Alveolar lavage fluid and Plasma	Hur et al. (2018)
Lung Adenocarcinoma	EGFR	PNA-PCR	Pleural effusion	Lee et al. (2018)
Pancreatic cancer	KRAS	ddPCR	Plasma	Allenson et al. (2017)
Pulmonary adenocarcinoma	EGFR	ddPCR	Bronchial Washing	Park et al. (2020)
Glioma	RET HIF2A VHL SDHB	Conventional PCR	Plasma	Wang et al. (2018)
non-small cell lung cancer	EGFR	ddPCR	Plasma	Castellanos-Rizaldos et al. (2018)
non-small cell lung cancer	EGFR	ddPCR	plasma and pleural fluid	Kim et al. (2021)
Lung Adenocarcinoma	EGFR	Quantitative PCR	Pleural Effusions	Qu et al. (2019)
Neuroblastoma	BRAF	Quantitative PCR	Plasma	Degli et al. (2021)
Bladder cancer	KRAS	ddPCR	Urine	Zhou et al. (2021)
prostate cancer	PTEN TP53	Quantitative PCR	Plasma	Lazaro-Ibanez et al. (2014)
Colorectal cancer	KRAS	ddPCR	Plasma	Lucchetti et al. (2021)
non-small cell lung cancer	EGFR	PNA-PCR	bronchoalveolar lavage fluid	Hur et al. (2019)
non-small cell lung cancer	EGFR	ddPCR	Plasma	Krug et al. (2018)
Pancreatic cancer	KRAS	ddPCR	Plasma	Bernard et al. (2019)
Glioma	IDH1	ddPCR	Plasma	Garcia-Romero et al. (2017)