Table 3.
Overall survival of GBM cohorts based on different score systems.
| Score | N (%) | Overall survival | P value | ||
|---|---|---|---|---|---|
| Variables | Definition | Mean ± SD | Median ± IQR | ||
| AGR-NLRa | |||||
| Score 0 | AGR>1.7 and NLR<2.0 | 5 (5.7) | 25.9 ± 13.4 | 22.5 (22.0) | reference |
| Score 1 | AGR<1.7 or NLR>2.0 | 30 (34.1) | 14.1 ± 7.0 | 16.2 (9.3) | 0.233 |
| Score 2 | AGR<1.7 and NLR>2.0 | 52 (59.1) | 9.3 ± 6.6 | 7.2 (9.2) | 0.003 |
| AGR-LMRb | |||||
| Score 0 | AGR>1.7 and LMR>2.3 | 15 (17.0) | 18.7 ± 10.5 | 16.7 (8.4) | reference |
| Score 1 | AGR<1.7 or LMR<2.3 | 55 (62.5) | 11.6 ± 7.1 | 10.0 (11.0) | 0.049 |
| Score 2 | AGR<1.7 and LMR<2.3 | 17 (19.3) | 7.0 ± 5.2 | 4.5 (6.7) | <0.001 |
| LMR-NLRc | |||||
| Score 0 | LMR>2.3 and NLR<2.0 | 23 (26.1) | 16.7 ± 9.9 | 16.6 (13.0) | reference |
| Score 1 | LMR<2.3 or NLR>2.0 | 43 (48.9) | 11.4 ± 7.2 | 10.2 (10.6) | 0.044 |
| Score 2 | LMR<2.3 and NLR>2.0 | 22 (25.0) | 8.2 ± 5.8 | 6.3 (10.1) | 0.001 |
| LMR-NLR-AGRd | |||||
| Score 0 | LMR>2.3 and NLR<2.0 and AGR>1.7 | 6 (6.8) | 24.3 ± 12.6 | 19.9 (16.8) | reference |
| Score 1 | LMR<2.3 or NLR>2.0 or AGR<1.7 | 25 (28.4) | 14.3 ± 7.2 | 16.1 (9.8) | 0.627 |
| Score 2 | LMR<2.3 and NLR>2.0, or LMR<2.3 and AGR<1.7, or NLR>2.0 and AGR<1.7 | 39 (44.3) | 10.7 ± 6.9 | 8.3 (10.5) | 0.022 |
| Score 3 | LMR<2.3 and NLR>2.0 and AGR<1.7 | 17 (19.3) | 7.0 ± 5·2 | 4.5 (6·7) | 0.001 |
a,b,c,d: the data was not available for one case in each score system.
NLR, neutrophil to lymphocyte ratio; PLR, platelet to lymphocyte ratio; LMR, lymphocyte to monocyte ratio; AGR, albumin to globulin ratio; SD, standard deviation; IQR, interquartile range.