Table 4.
Regression analysis results for determination of MET, LIN and EMP in spiked human plasma. (a, intercept; b, slope; r, correlation coefficient; Sa, standard deviation of intercept; Sb, standard deviation of slope; Sy/x, residual standard deviation; LOD, limit of detection; LOQ, limit of quantitation.)
| parameters | MET | EMP | LIN |
|---|---|---|---|
| concentration range (µg ml−1) | 0.1–2 | 0.05–2 | 0.05–2 |
| r | 0.99998 | 0.99999 | 0.99998 |
| a | 0.006 | 7.60 × 10−4 | 0.022 |
| b | 0.446 | 0.436 | 1.142 |
| Sa | 0.002 | 9.20 × 10−4 | 0.005 |
| Sb | 0.002 | 8.92 × 10−4 | 0.004 |
| S(y/x) | 0.003 | 0.001 | 0.007 |
| LOD | 0.017 | 0.007 | 0.013 |
| LOQ | 0.052 | 0.021 | 0.040 |