Table 2.

Results of meta-analysis with cut-offs, sensitivity, and specificity for all included studies with demographic details

Author	TP	FN	FP	TN	Cut-off (SN+)	Sens	Spec
Alonso-Canovas et al. 2014 [19]	80	16	5	45	0.21 cm2	83.0	90.0
Bartova et al. 2014 [20]	26	3	2	9	0.25 cm2	89.6	81.8
Budisic et al. 2009 [16]	64	6	4	26	0.20 cm2	91.4	86.7
Cardaioli et al. 2019 [12]	56	18	10	26	0.14 cm2	75.0	72.0
Chen et al. 2012 [29]	18	19	4	22	0.20 cm2	48.7	84.6
Chitsaz et al. 2013 [21]	39	4	7	36	0.20 cm2	90.7	83.7
Doepp et al. 2008 [22]	36	10	2	23	0.20 cm2	78.0	92.0
Grippe et al. 2018 [13]	37	2	1	10	0.20 cm2	93.9	95.2
Jesus-Ribeiro et al. 2016 [25]	28	4	1	25	0.24 cm2	87.5	96.2
Kim et al. 2012 [27]	35	12	8	56	0.20 cm2	74.5	87.5
Lauckaite et al. 2012 [14]	66	5	26	32	0.20 cm2	91.8	55.2
Lauckaite et al. 2014 [15]	106	35	49	67	0.20 cm2	75.0	58.0
Lopez Hernandez et al. 2015 [18]	21	9	2	19	0.24 cm2	83.3	90.5
Richter et al. 2017 [17]	28	3	2	14	0.20 cm2	90.3	87.5
Stenc Bradvica et al. 2015 [26]	56	3	6	45	0.20 cm2	94.9	88.2
Stockner et al. 2007 [23]	75	25	7	37	0.24 cm2	75.0	84.0
Tao et al. 2020 [24]	108	11	10	96	0.20 cm2	91.2	90.5
Wang et al. 2021 [28]	162	38	19	71	0.25 cm2	81.0	75.4

FN, false negative; FP, false positive; Sens, sensitivity; SN+, substantia nigra hyperintensity; Spec, specificity; TN, true negative; TP, true positive.