Figure 2.

Siglec-7 expression is increased on NK cells from BMAs of patients with MM, while Siglec-9 expression is decreased. CD56⁺/CD3^- NK cells sourced from peripheral blood of healthy donors (black) and from BMAs of patients with MM (red) were stained for the expression of (A) Siglec-7 and (B) Siglec-9. Data analyzed using Mann-Whitney unpaired t-test. Graphs represent both mean Siglec-7⁺ NK cells and mean MFI of Siglec-7⁺ NK cells as well as individual values for each sample. n = 5 for healthy donor peripheral blood-derived NK cells, and n = 6 for MM patient BMA-derived NK cells. **P < .01; ns, not significant.