Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Generation of Sirt1d/d mice. Sirt1d/d female mice do not express SIRT1 in any uterine cell layer. (A) The schematic shows the strategy for generating Pgrcre/+Sirt1f/f (Sirt1d/d) mice. (B) Relative expression of uterine Sirt1 at GD 5.5, mRNA normalized to Rpl7 (n = 5, *p < 0.05). The results represent the mean ± SEM. *p < 0.05. (C) Uterine SIRT1 protein expression at GD 5.5 normalized to ACTIN. (D) Representative images of SIRT1 IHC in uterine tissue at GD 5.5 (n = 3).
