Table II.
Virucidal efficacy of CAC-717 against SARS-CoV-2.
| Viral titer (TCID50/ml) | |||
|---|---|---|---|
| Strain | Variant type | Distilled water | CAC-717 |
| SARS-CoV-2/WK-521 | Original | 4.9 | ≤0.6 |
| SARS-CoV-2/KH-1/2021 | Original | 5.0 | ≤0.6 |
| hCoV-19/Japan/QK002/2020 | α | 4.2 | ≤0.6 |
| hCoV-19/Japan/TY8-612/2021 | β | 4.8 | ≤0.6 |
| hCoV-19/Japan/TY7-501/2021 | γ | 4.4 | ≤0.7 |
| SARS-CoV-2/KH-25/2021 | δ | 4.9 | ≤0.6 |
Aliquots of virus were mixed with 49 volumes of CAC-717, incubated for 5 min, and SARS-CoV-2 titers were measured (22). TCID50, tissue culture infectious dose.