Table IV.
Univariate analysis of all-cause and cardiovascular mortality and its association with categorical and continuous variables*
| Variable | All-cause mortality | Cardiovascular mortality | ||
|---|---|---|---|---|
| RR (95% CI) | P-value | RR (95% CI) | P-value | |
| Categorical variables: | ||||
| Male gender | 1.339 (0.880–2.036) | 0.171 | 1.224 (0.758–1.976) | 0.408 |
| NYHA ≥ III before TAVI | 1.605 (1.022–2.520) | 0.038 | 2.203 (1.276–3.802) | 0.004 |
| Diabetes mellitus | 1.357 (0.897–2.054) | 0.147 | 1.362 (0.849–2.184) | 0.198 |
| Arterial hypertension | 0.877 (0.523–1.472) | 0.619 | 0.951 (0.520–1.739) | 0.870 |
| Atrial fibrillation | 2.108 (1.395–3.188) | < 0.001 | 1.901 (1.185–3.050) | 0.007 |
| Coronary artery disease | 1.329 (0.879–2.010) | 0.176 | 1.284 (0.802–2.056) | 0.297 |
| Pacemaker before TAVI | 1.243 (0.714–2.164) | 0.441 | 1.279 (0.688–2.381) | 0.436 |
| Pacemaker after TAVI | 0.994 (0.598–1.651) | 0.980 | 0.771 (0.429–1.385) | 0.730 |
| Balloon valvuloplasty during TAVI | 0.844 (0.537–1.327) | 0.463 | 0.974 (0.584–1.625) | 0.920 |
| Open surgical access | 1.329 (0.837–2.111) | 0.226 | 1.344 (0.794–2.276) | 0.270 |
| Creatinine worsening after the procedure | 1.606 (1.042–2.473) | 0.030 | 1.572 (0.959–2.578) | 0.071 |
| Continuous variables: | ||||
| Age | 1.050 (1.011–1.090) | 0.011 | 1.049 (1.005–1.095) | 0.028 |
| Body mass index | 0.942 (0.903–0.982) | 0.005 | 0.958 (0.915–1.002) | 0.063 |
| Creatinine before TAVI† | 1.029 (1.012 - 1.047) | 0.001 | 1.029 (1.008–1.050) | 0.006 |
| Creatinine after TAVI† | 1.029 (1.015–1.045) | < 0.001 | 1.030 (1.013–1.047) | < 0.001 |
| Hemoglobin before TAVI† | 0.759 (0.669–0.861) | < 0.001 | 0.750 (0.650–0.867) | < 0.001 |
| Hemoglobin after TAVI† | 0.826 (0.722–0.945) | 0.005 | 0.818 (0.701–0.956) | 0.011 |
| Platelets before TAVI† | 1.007 (0.977–1.040) | 0.643 | 1.007 (0.972–1.044) | 0.699 |
| Platelets after TAVI† | 1.003 (0.961–1.045) | 0.902 | 0.984 (0.935–1.036) | 0.543 |
| Troponin after TAVI‡ | 1.000 (0.995–1.006) | 0.874 | 1.001 (0.996–1.007) | 0.564 |
| Agatston score‡ | 1.000 (0.978–1.022) | 0.980 | 1.002 (0.971–1.026) | 0.901 |
| STS score | 1.047 (1.022–1.073) | < 0.001 | 1.047 (1.020–1.075) | < 0.001 |
| Mean aortic valve gradient before TAVI | 1.001 (0.986–1.017) | 0.901 | 1.002 (0.984–1.020) | 0.843 |
| Mean aortic valve gradient after TAVI | 1.012 (0.967–1.060) | 0.600 | 0.999 (0.946–1.055) | 0.967 |
| Aortic valve area before TAVI | 1.523 (0.492–4.172) | 0.466 | 1.085 (0.297–3.973) | 0.901 |
| Left ventricle ejection fraction | 0.991 (0.976–1.006) | 0.222 | 0.991 (0.974–1.008) | 0.297 |
| Septal wall thickness | 1.091 (0.989–1.204) | 0.081 | 1.115 (1.000–1.244) | 0.050 |
| Inferior wall thickness | 1.185 (1.047–1.342) | 0.007 | 1.253 (1.088–1.442) | 0.002 |
*
One-unit increase
†
ten-unit increase
‡
hundred-unit increase.