TABLE 2.
Hypothetical patient-level data for trial illustration
| BOIN12 | TITE-BOIN12 | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||||||
| ID | Dose | YT | YE | Day | XT | XE | ID | Dose | YT | YE | Day | XT | XE |
| 1 | 1 | 0 | 0 | 1 | - | - | 1 | 1 | 0 | 0 | 1 | - | - |
| 2 | 1 | 0 | 0 | 11 | - | - | 2 | 1 | 0 | 0 | 11 | - | - |
| 3 | 1 | 0 | 0 | 21 | - | - | 3 | 1 | 0 | 0 | 21 | - | - |
| 4 | 2 | 0 | 1 | 82 | - | 40 | 4 | 2 | 0 | 1 | 72 | - | 40 |
| 5 | 2 | 1 | 0 | 92 | 30 | - | 5 | 2 | 1 | 0 | 82 | 30 | - |
| 6 | 2 | 0 | 0 | 102 | - | - | 6 | 2 | 0 | 0 | 92 | - | - |
| 7 | 3 | 0 | 1 | 163 | - | 40 | 7 | 3 | 0 | 1 | 143 | - | 40 |
| 8 | 3 | 1 | 0 | 173 | 25 | - | 8 | 3 | 1 | 0 | 153 | 25 | - |
| 9 | 3 | 0 | 0 | 183 | - | - | 9 | 3 | 0 | 0 | 163 | - | - |
| 10 | 4 | 0 | 0 | 244 | - | - | 10 | 4 | 0 | 0 | 214 | - | - |
| 11 | 4 | 1 | 0 | 254 | 40 | - | 11 | 4 | 1 | 0 | 224 | 40 | - |
| 12 | 4 | 1 | 0 | 264 | 35 | - | 12 | 4 | 1 | 0 | 234 | 35 | - |
| 13 | 3 | 1 | 1 | 325 | 25 | 30 | 13 | 3 | 1 | 1 | 285 | 25 | 30 |
| 14 | 3 | 0 | 1 | 335 | - | 55 | 14 | 3 | 0 | 1 | 295 | - | 55 |
| 15 | 3 | 0 | 0 | 345 | - | - | 15 | 3 | 0 | 0 | 305 | - | - |
| 16 | 3 | 0 | 1 | 396 | - | 50 | 16 | 3 | 0 | 1 | 316 | - | 50 |
| 17 | 3 | 0 | 1 | 406 | - | 50 | 17 | 3 | 0 | 1 | 326 | - | 50 |
| 18 | 3 | 1 | 0 | 416 | 30 | - | 18 | 3 | 1 | 0 | 336 | 30 | - |
ID: patient ID; Day: day of enrollment.