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. 2021 Sep 23;163(7):e812–e820. doi: 10.1097/j.pain.0000000000002497

Table 2.

Use of sleep and pain medications in chronic pain patients sleeping normally or with sleep problems.

n* Sleeping normally Sleep problems P
61 198
Using prescribed sleep medication regularly (3 or more nights per week): n (%) 2 (3.3) 55 (27.8) <0.001
Reported use of: n (%)
 Benzodiazepine derivatives
  Temazepam 0 (0.0) 11 (5.5) 0.06
  Diazepam 0 (0.0) 9 (4.5) 0.12
  Zolpidem 0 (0.0) 25 (12.6) 0.004
 Melatonin 1 (1.6) 25 (12.6) 0.01
 Quetiapine 0 (0.0) 11 (5.5) 0.07
 Mirtazapine 1 (1.6) 11 (5.5) 0.31
Pain medications in regular use: n (%)
 Paracetamol (acetaminophen) 5 (8.2) 34 (17.2) 0.09
 NSAIDs 3 (4.9) 48 (24.2) 0.001
 Amitriptyline/nortriptyline 5 (8.2) 39 (19.7) 0.04
 Venlafaxine/duloxetine 1 (1.6) 22 (11.1) 0.02
 Carbamazepine/oxcarbazepine/lamotrigine 8 (13.1) 7 (3.5) 0.01
 Gabapentin/pregabalin 7 (11.5) 51 (25.8) 0.02
 Codeine/tramadol 2 (3.3) 52 (26.3) <0.001
 Buprenorphine 4 (6.6) 20 (10.1) 0.40
 Oxycodone/morphine/hydromorphone/fentanyl 0 (0.0) 6 (3.0) 0.34
*

Differences in n with respect to original categorization are due to missing data. Bold indicates P values <0.05.

NSAIDs, nonsteroidal anti-inflammatory drugs.