Fig. 6.

HCQ rescues the expression levels of CD81, leading to increase the apoptosis of MDSCs. A, B qRT-PCR (A) and Western blotting (B) was used to detect the expression level of CD81 in BM-derived MDSCs (n = 4). C The number of BM-derived MDSCs was determined by FACS (n = 4). D The effects of HCQ on the apoptosis of BM-MDSCs after interfering CD81 were measured by FACS (n = 4). Data are presented as the mean ± standard error of the mean (SEM). *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001