Table 3.
Linear regression coefficients and their 95% confidence intervals for the difference of microbial relative abundance and alpha diversity indices in high intake group compared to low intake group
| Dietary feature | Chao1 a | Shannon a | Simpson a | F/B ratio | Bacteroidetes | Firmicutes | Bacteroidia | Clostridia | Bacteroidales | Clostridiales | Bacteroidaceae | Rikenellaceae | Alistipes | Bacteroides |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Univariable model | ||||||||||||||
| Food groups | ||||||||||||||
| Cereals and grains | 0.08 (-0.06, 0.21) | 0.06 (-0.05, 0.16) | 0.05 (-0.04, 0.13) | -3.48 (-17.4, 10.4) | 0.06 (-0.02, 0.14) | -0.06 (-0.13, 0.01) | 0.06 (-0.02, 0.14) | -0.04 (-0.11, 0.03) | 0.06 (-0.02, 0.14) | -0.04 (-0.11, 0.03) | 0.01 (-0.07, 0.09) | 0.02 (-0.03, 0.07) | 0.02 (-0.03, 0.07) | 0.01 (-0.08, 0.09) |
| Potatoes and starches | -0.09 (-0.22, 0.04) | -0.08 (-0.18, 0.03) | -0.05 (-0.14, 0.03) | 2.71 (-11.2, 16.6) | 0 (-0.08, 0.07) | -0.03 (-0.11, 0.04) | 0 (-0.08, 0.07) | -0.05 (-0.12, 0.02) | 0 (-0.08, 0.07) | -0.05 (-0.12, 0.02) | -0.01 (-0.09, 0.07) | -0.04 (-0.08, 0.01) | -0.04 (-0.08, 0.01) | -0.01 (-0.09, 0.07) |
| Sugars and sweets | 0.07 (-0.06, 0.21) | -0.02 (-0.13, 0.09) | -0.01 (-0.10, 0.07) | -10.2 (-23.97, 3.64) | 0.03 (-0.05, 0.11) | -0.07 (-0.14, 0.01) | 0.03 (-0.05, 0.11) | -0.06 (-0.13, 0.01) | 0.03 (-0.05, 0.11) | -0.06 (-0.13, 0.01) | -0.02 (-0.10, 0.06) | -0.03 (-0.08, 0.02) | -0.03 (-0.08, 0.02) | -0.02 (-0.10, 0.06) |
| Legumes | -0.03 (-0.16, 0.11) | -0.06 (-0.17, 0.04) | -0.04 (-0.13, 0.04) | 3.08 (-10.84, 17) | -0.03 (-0.11, 0.05) | 0 (-0.08, 0.07) | -0.03 (-0.11, 0.05) | -0.03 (-0.10, 0.04) | -0.03 (-0.11, 0.05) | -0.03 (-0.10, 0.04) | 0.03 (-0.05, 0.11) | -0.02 (-0.07, 0.03) | -0.02 (-0.07, 0.03) | 0.02 (-0.06, 0.11) |
| Seeds and nuts | 0.1 (-0.03, 0.23) | 0.1 (0, 0.21) | 0.07 (-0.01, 0.15) | -9.68 (-23.5, 4.13) | -0.02 (-0.10, 0.06) | -0.01 (-0.09, 0.06) | -0.02 (-0.10, 0.06) | 0 (-0.07, 0.07) | -0.02 (-0.10, 0.06) | 0 (-0.07, 0.07) | 0.02 (-0.06, 0.10) | 0.01 (-0.04, 0.05) | 0.01 (-0.04, 0.06) | 0.03 (-0.06, 0.11) |
| Vegetables | -0.03 (-0.16, 0.10) | -0.02 (-0.12, 0.09) | -0.02 (-0.11, 0.06) | 2.98 (-10.9, 16.9) | -0.04 (-0.12, 0.04) | 0.03 (-0.05, 0.10) | -0.04 (-0.12, 0.04) | 0.01 (-0.06, 0.08) | -0.04 (-0.12, 0.04) | 0.01 (-0.06, 0.08) | 0 (-0.08, 0.08) | -0.04 (-0.08, 0.01) | -0.04 (-0.08, 0.01) | 0 (-0.08, 0.08) |
| Mushrooms | 0.1 (-0.03, 0.23) | 0.04 (-0.07, 0.14) | 0.02 (-0.06, 0.10) | -9.46 (-23.3, 4.36) | 0 (-0.08, 0.08) | 0 (-0.08, 0.07) | 0 (-0.08, 0.08) | 0 (-0.07, 0.07) | 0 (-0.08, 0.08) | 0 (-0.07, 0.07) | 0.03 (-0.05, 0.11) | 0 (-0.05, 0.05) | 0 (-0.05, 0.05) | 0.03 (-0.05, 0.11) |
| Fruits | 0.09 (-0.04, 0.22) | 0.08 (-0.03, 0.18) | 0.05 (-0.03, 0.14) | -9.57 (-23.4, 4.25) | 0.01 (-0.07, 0.09) | -0.03 (-0.10, 0.04) | 0.01 (-0.07, 0.09) | -0.02 (-0.09, 0.05) | 0.01 (-0.07, 0.09) | -0.02 (-0.09, 0.05) | 0.01 (-0.07, 0.09) | 0.03 (-0.02, 0.07) | 0.03 (-0.02, 0.07) | 0.01 (-0.07, 0.09) |
| Meat and poultry | 0.08 (-0.05, 0.21) | 0.02 (-0.09, 0.13) | 0 (-0.08, 0.08) | -9.32 (-23.1, 4.51) | 0.02 (-0.06, 0.10) | -0.01 (-0.09, 0.06) | 0.02 (-0.06, 0.10) | -0.01 (-0.08, 0.06) | 0.02 (-0.06, 0.10) | -0.01 (-0.08, 0.06) | -0.02 (-0.10, 0.06) | 0.05 (0, 0.10) | 0.05 (0, 0.10) | -0.02 (-0.10, 0.06) |
| Eggs | 0.06 (-0.08, 0.19) | 0.02 (-0.09, 0.13) | 0 (-0.08, 0.08) | -9.25 (-23.1, 4.58) | 0.02 (-0.06, 0.10) | 0.04 (-0.03, 0.12) | 0.02 (-0.06, 0.10) | 0.04 (-0.03, 0.11) | 0.02 (-0.06, 0.10) | 0.04 (-0.03, 0.11) | -0.02 (-0.10, 0.06) | -0.02 (-0.07, 0.02) | -0.02 (-0.07, 0.02) | -0.02 (-0.10, 0.06) |
| Fish and shellfish | 0.03 (-0.10, 0.17) | -0.03 (-0.14, 0.07) | -0.05 (-0.13, 0.03) | -9.48 (-23.3, 4.34) | 0.07 (-0.01, 0.15) | -0.05 (-0.12, 0.03) | 0.07 (-0.01, 0.15) | -0.05 (-0.12, 0.02) | 0.07 (-0.01, 0.15) | -0.05 (-0.12, 0.02) | 0.08 (0, 0.16) | -0.02 (-0.07, 0.03) | -0.02 (-0.07, 0.03) | 0.08 (0, 0.16) |
| Seaweed | -0.06 (-0.19, 0.07) | -0.07 (-0.17, 0.04) | -0.07 (-0.15, 0.02) | 9.35 (-4.48, 23.2) | -0.03 (-0.11, 0.05) | 0 (-0.07, 0.08) | -0.03 (-0.11, 0.05) | -0.01 (-0.08, 0.06) | -0.03 (-0.11, 0.05) | -0.01 (-0.08, 0.06) | 0 (-0.08, 0.08) | -0.06 (-0.11, -0.01) | -0.06 (-0.11, -0.02) | 0 (-0.08, 0.08) |
| Milk and dairy | -0.04 (-0.17, 0.09) | -0.08 (-0.19, 0.02) | -0.06 (-0.14, 0.02) | 2.54 (-11.4, 16.5) | 0.04 (-0.04, 0.12) | -0.01 (-0.08, 0.07) | 0.04 (-0.04, 0.12) | -0.01 (-0.08, 0.06) | 0.04 (-0.04, 0.12) | -0.01 (-0.08, 0.06) | 0.04 (-0.04, 0.12) | -0.04 (-0.09, 0.01) | -0.04 (-0.09, 0.01) | 0.04 (-0.04, 0.13) |
| Oils and fats | 0.07 (-0.06, 0.20) | 0.04 (-0.06, 0.15) | 0.05 (-0.04, 0.13) | -9.72 (-23.5, 4.1) | -0.01 (-0.09, 0.07) | -0.02 (-0.10, 0.05) | -0.01 (-0.09, 0.07) | -0.02 (-0.09, 0.05) | -0.01 (-0.09, 0.07) | -0.02 (-0.09, 0.05) | -0.08 (-0.16, 0) | -0.01 (-0.06, 0.04) | -0.01 (-0.06, 0.04) | -0.08 (-0.16, 0) |
| Beverages | 0.06 (-0.07, 0.20) | -0.01 (-0.12, 0.09) | -0.02 (-0.11, 0.06) | -9.71 (-23.5, 4.1) | 0.08 (0, 0.16) | -0.05 (-0.12, 0.03) | 0.08 (0, 0.16) | -0.03 (-0.10, 0.05) | 0.08 (0, 0.16) | -0.03 (-0.10, 0.05) | 0.02 (-0.06, 0.10) | 0.01 (-0.04, 0.06) | 0.01 (-0.04, 0.06) | 0.03 (-0.06, 0.11) |
| Seasonings | 0.08 (-0.06, 0.21) | 0.06 (-0.04, 0.17) | 0.04 (-0.04, 0.12) | -9.34 (-23.2, 4.48) | -0.02 (-0.10, 0.06) | -0.01 (-0.08, 0.07) | -0.02 (-0.10, 0.06) | -0.01 (-0.08, 0.06) | -0.02 (-0.10, 0.06) | -0.01 (-0.08, 0.06) | -0.07 (-0.14, 0.01) | 0.05 (0, 0.09) | 0.05 (0, 0.09) | -0.07 (-0.15, 0.01) |
| Macronutrients | ||||||||||||||
| Plant protein | 0.02 (-0.12, 0.15) | 0.02 (-0.08, 0.13) | 0.01 (-0.07, 0.10) | 2.75 (-11.2, 16.7) | -0.04 (-0.12, 0.04) | -0.01 (-0.08, 0.07) | -0.04 (-0.12, 0.04) | -0.02 (-0.09, 0.05) | -0.04 (-0.12, 0.04) | -0.02 (-0.09, 0.05) | -0.03 (-0.11, 0.05) | -0.04 (-0.08, 0.01) | -0.04 (-0.09, 0.01) | -0.04 (-0.12, 0.04) |
| Animal protein | 0.04 (-0.09, 0.18) | 0.03 (-0.08, 0.14) | 0.01 (-0.08, 0.09) | -9.07 (-22.9, 4.76) | -0.03 (-0.10, 0.05) | 0.04 (-0.03, 0.12) | -0.03 (-0.10, 0.05) | 0.04 (-0.03, 0.11) | -0.03 (-0.10, 0.05) | 0.04 (-0.03, 0.11) | -0.04 (-0.12, 0.04) | 0.01 (-0.03, 0.06) | 0.01 (-0.03, 0.06) | -0.04 (-0.12, 0.04) |
| Plant fat | -0.02 (-0.15, 0.12) | 0.01 (-0.10, 0.11) | 0.01 (-0.07, 0.09) | -9.08 (-22.9, 4.75) | -0.03 (-0.11, 0.05) | 0.02 (-0.06, 0.09) | -0.03 (-0.11, 0.05) | 0.01 (-0.06, 0.08) | -0.03 (-0.11, 0.05) | 0.01 (-0.06, 0.08) | -0.01 (-0.09, 0.07) | -0.02 (-0.07, 0.02) | -0.02 (-0.07, 0.02) | -0.01 (-0.10, 0.07) |
| Animal fat | 0.04 (-0.09, 0.18) | 0.03 (-0.08, 0.14) | 0.01 (-0.07, 0.09) | -9.18 (-23.0, 4.65) | -0.01 (-0.08, 0.07) | 0.03 (-0.05, 0.10) | -0.01 (-0.08, 0.07) | 0.02 (-0.05, 0.09) | -0.01 (-0.08, 0.07) | 0.02 (-0.05, 0.09) | -0.01 (-0.09, 0.07) | -0.01 (-0.06, 0.04) | -0.01 (-0.06, 0.04) | -0.01 (-0.09, 0.07) |
| Carbohydrates | -0.09 (-0.22, 0.04) | -0.06 (-0.16, 0.05) | -0.02 (-0.10, 0.06) | 8.97 (-4.87, 22.8) | 0.02 (-0.06, 0.10) | -0.03 (-0.10, 0.05) | 0.02 (-0.06, 0.10) | -0.02 (-0.09, 0.05) | 0.02 (-0.06, 0.10) | -0.02 (-0.09, 0.05) | 0.02 (-0.06, 0.10) | -0.04 (-0.08, 0.01) | -0.04 (-0.08, 0.01) | 0.02 (-0.06, 0.11) |
| Fiber | 0.01 (-0.13, 0.14) | 0.02 (-0.09, 0.12) | 0 (-0.08, 0.08) | 3.2 (-10.7, 17.1) | -0.08 (-0.16, 0) | 0.05 (-0.02, 0.13) | -0.08 (-0.16, 0) | 0.04 (-0.03, 0.11) | -0.08 (-0.16, 0) | 0.04 (-0.03, 0.11) | -0.04 (-0.12, 0.04) | -0.03 (-0.07, 0.02) | -0.03 (-0.07, 0.02) | -0.04 (-0.12, 0.04) |
| Fatty acids | ||||||||||||||
| SFAs | -0.03 (-0.16, 0.11) | -0.07 (-0.18, 0.04) | -0.07 (-0.15, 0.01) | -9.61 (-23.4, 4.21) | 0.05 (-0.03, 0.13) | -0.02 (-0.09, 0.05) | 0.05 (-0.03, 0.13) | -0.01 (-0.08, 0.06) | 0.05 (-0.03, 0.13) | -0.01 (-0.08, 0.06) | 0.02 (-0.06, 0.10) | -0.02 (-0.06, 0.03) | -0.02 (-0.06, 0.03) | 0.02 (-0.06, 0.10) |
| MUFAs | -0.04 (-0.18, 0.09) | -0.06 (-0.16, 0.05) | -0.06 (-0.15, 0.02) | -9.49 (-23.3, 4.33) | 0.02 (-0.06, 0.10) | 0 (-0.08, 0.07) | 0.02 (-0.06, 0.10) | 0 (-0.07, 0.07) | 0.02 (-0.06, 0.10) | 0 (-0.07, 0.07) | 0.02 (-0.06, 0.10) | 0 (-0.04, 0.05) | 0 (-0.04, 0.05) | 0.03 (-0.06, 0.11) |
| PUFAs | 0.07 (-0.06, 0.21) | 0.05 (-0.06, 0.15) | 0.01 (-0.07, 0.09) | -9.29 (-23.1, 4.53) | -0.03 (-0.10, 0.05) | 0.06 (-0.02, 0.13) | -0.03 (-0.10, 0.05) | 0.06 (-0.01, 0.13) | -0.03 (-0.10, 0.05) | 0.06 (-0.01, 0.13) | -0.05 (-0.13, 0.03) | 0 (-0.04, 0.05) | 0 (-0.04, 0.05) | -0.05 (-0.13, 0.03) |
| Multivariable model | ||||||||||||||
| Food groups | ||||||||||||||
| Cereals and grains | 0.08 (-0.07, 0.23) | 0.06 (-0.05, 0.18) | 0.05 (-0.04, 0.13) | -2.74 (-18.1, 12.6) | 0.06 (-0.02, 0.15) | -0.07 (-0.15, 0.02) | 0.06 (-0.02, 0.15) | -0.05 (-0.13, 0.03) | 0.06 (-0.02, 0.15) | -0.05 (-0.13, 0.03) | -0.01 (-0.10, 0.08) | 0.03 (-0.02, 0.08) | 0.03 (-0.02, 0.08) | -0.01 (-0.1, 0.08) |
| Potatoes and starches | -0.09 (-0.24, 0.06) | -0.08 (-0.20, 0.04) | -0.05 (-0.14, 0.04) | 1.33 (-14.4, 17.1) | -0.01 (-0.10, 0.07) | -0.03 (-0.11, 0.06) | -0.01 (-0.1, 0.07) | -0.05 (-0.13, 0.03) | -0.01 (-0.10, 0.07) | -0.05 (-0.13, 0.03) | -0.02 (-0.11, 0.07) | -0.01 (-0.06, 0.04) | -0.01 (-0.07, 0.04) | -0.02 (-0.11, 0.07) |
| Sugars and sweets | 0.09 (-0.07, 0.24) | 0.01 (-0.11, 0.13) | 0.01 (-0.08, 0.10) | -7.6 (-23.5, 8.30) | 0 (-0.09, 0.09) | -0.05 (-0.13, 0.04) | 0 (-0.09, 0.09) | -0.03 (-0.12, 0.05) | 0 (-0.09, 0.09) | -0.03 (-0.12, 0.05) | -0.03 (-0.12, 0.06) | -0.03 (-0.08, 0.03) | -0.03 (-0.08, 0.02) | -0.03 (-0.12, 0.06) |
| Legumes | -0.03 (-0.18, 0.11) | -0.06 (-0.17, 0.05) | -0.04 (-0.13, 0.04) | 5.69 (-9.20, 20.5) | -0.04 (-0.12, 0.05) | 0.01 (-0.07, 0.09) | -0.04 (-0.12, 0.05) | -0.02 (-0.1, 0.06) | -0.04 (-0.12, 0.05) | -0.02 (-0.1, 0.06) | 0.01 (-0.08, 0.09) | -0.02 (-0.06, 0.03) | -0.02 (-0.07, 0.03) | 0 (-0.08, 0.09) |
| Seeds and nuts | 0.10 (-0.04, 0.25) | 0.10 (-0.01, 0.21) | 0.07 (-0.01, 0.16) | -10.6 (-25.5, 4.4) | -0.02 (-0.10, 0.07) | -0.02 (-0.1, 0.06) | -0.02 (-0.10, 0.07) | -0.01 (-0.08, 0.07) | -0.02 (-0.10, 0.07) | -0.01 (-0.08, 0.07) | 0.02 (-0.06, 0.11) | 0.01 (-0.04, 0.06) | 0.01 (-0.04, 0.06) | 0.03 (-0.06, 0.12) |
| Vegetables | -0.04 (-0.19, 0.11) | -0.04 (-0.15, 0.08) | -0.04 (-0.12, 0.05) | 2.52 (-12.61, 17.7) | -0.03 (-0.11, 0.06) | 0.02 (-0.07, 0.10) | -0.03 (-0.11, 0.06) | 0 (-0.08, 0.08) | -0.03 (-0.11, 0.06) | 0 (-0.08, 0.08) | 0.02 (-0.07, 0.1) | -0.05 (-0.10, 0) | -0.05 (-0.10, 0) | 0.02 (-0.07, 0.11) |
| Mushrooms | 0.09 (-0.06, 0.24) | 0.04 (-0.08, 0.15) | 0.02 (-0.07, 0.11) | -10.1 (-25.3, 5.10) | 0.01 (-0.08, 0.10) | -0.02 (-0.10, 0.07) | 0.01 (-0.08, 0.10) | -0.01 (-0.08, 0.07) | 0.01 (-0.08, 0.10) | -0.01 (-0.08, 0.07) | 0.02 (-0.07, 0.11) | -0.01 (-0.06, 0.04) | -0.01 (-0.06, 0.04) | 0.02 (-0.07, 0.11) |
| Fruits | 0.10 (-0.05, 0.25) | 0.09 (-0.02, 0.20) | 0.07 (-0.02, 0.15) | -8.59 (-23.7, 6.50) | 0.01 (-0.08, 0.09) | -0.03 (-0.11, 0.05) | 0.01 (-0.08, 0.09) | -0.01 (-0.09, 0.06) | 0.01 (-0.08, 0.09) | -0.01 (-0.09, 0.06) | 0.03 (-0.06, 0.12) | 0.04 (-0.01, 0.09) | 0.04 (-0.01, 0.09) | 0.03 (-0.06, 0.12) |
| Meat and poultry | 0.11 (-0.05, 0.26) | 0.01 (-0.11, 0.13) | -0.01 (-0.1, 0.09) | -10.0 (-26.1, 5.97) | 0.03 (-0.06, 0.12) | -0.03 (-0.12, 0.05) | 0.03 (-0.06, 0.12) | -0.02 (-0.11, 0.06) | 0.03 (-0.06, 0.12) | -0.02 (-0.11, 0.06) | -0.01 (-0.1, 0.08) | 0.03 (-0.02, 0.08) | 0.03 (-0.02, 0.08) | -0.01 (-0.11, 0.08) |
| Eggs | 0.07 (-0.08, 0.22) | 0.02 (-0.1, 0.13) | 0 (-0.09, 0.09) | -12.4 (-27.3, 2.49) | 0.03 (-0.05, 0.12) | 0.03 (-0.05, 0.11) | 0.03 (-0.05, 0.12) | 0.04 (-0.04, 0.11) | 0.03 (-0.05, 0.12) | 0.04 (-0.04, 0.11) | -0.02 (-0.11, 0.07) | -0.04 (-0.09, 0.01) | -0.04 (-0.09, 0.01) | -0.02 (-0.11, 0.07) |
| Fish and shellfish | 0.03 (-0.12, 0.18) | -0.05 (-0.17, 0.06) | -0.07 (-0.16, 0.02) | -8.69 (-23.7, 6.34) | 0.07 (-0.01, 0.16) | -0.06 (-0.14, 0.03) | 0.07 (-0.01, 0.16) | -0.06 (-0.14, 0.02) | 0.07 (-0.01, 0.16) | -0.06 (-0.13, 0.02) | 0.10 (0.01, 0.18) | -0.02 (-0.07, 0.02) | -0.03 (-0.08, 0.02) | 0.1 (0.01, 0.18) |
| Seaweed | -0.06 (-0.21, 0.09) | -0.06 (-0.17, 0.05) | -0.06 (-0.15, 0.03) | 8.91 (-6.08, 23.9) | -0.05 (-0.14, 0.03) | 0.01 (-0.07, 0.09) | -0.05 (-0.13, 0.03) | 0 (-0.08, 0.08) | -0.05 (-0.13, 0.03) | 0 (-0.08, 0.08) | 0 (-0.09, 0.09) | -0.06 (-0.11, -0.02) | -0.07 (-0.11, -0.02) | 0 (-0.09, 0.09) |
| Milk and dairy | -0.03 (-0.18, 0.11) | -0.07 (-0.18, 0.04) | -0.05 (-0.13, 0.04) | 2.98 (-12.0, 17.9) | 0.02 (-0.07, 0.10) | 0 (-0.08, 0.09) | 0.02 (-0.07, 0.10) | 0 (-0.08, 0.07) | 0.02 (-0.07, 0.10) | 0 (-0.08, 0.07) | 0.04 (-0.04, 0.13) | -0.04 (-0.08, 0.01) | -0.04 (-0.09, 0.01) | 0.04 (-0.04, 0.13) |
| Oils and fats | 0.05 (-0.11, 0.20) | 0.03 (-0.09, 0.15) | 0.04 (-0.05, 0.14) | -5.8 (-21.7, 10.1) | -0.04 (-0.13, 0.05) | -0.01 (-0.10, 0.08) | -0.04 (-0.13, 0.05) | -0.01 (-0.09, 0.07) | -0.04 (-0.13, 0.05) | -0.01 (-0.09, 0.07) | -0.08 (-0.17, 0.01) | -0.02 (-0.07, 0.03) | -0.02 (-0.07, 0.03) | -0.08 (-0.17, 0.01) |
| Beverages | 0.07 (-0.07, 0.22) | -0.02 (-0.13, 0.09) | -0.03 (-0.12, 0.05) | -11.6 (-26.3, 3.10) | 0.10 (0.02, 0.18) | -0.07 (-0.15, 0.01) | 0.10 (0.02, 0.18) | -0.04 (-0.12, 0.04) | 0.10 (0.02, 0.18) | -0.04 (-0.12, 0.04) | 0.02 (-0.06, 0.11) | 0 (-0.05, 0.05) | 0 (-0.05, 0.05) | 0.02 (-0.06, 0.11) |
| Seasonings | 0.06 (-0.09, 0.21) | 0.03 (-0.08, 0.14) | 0.02 (-0.07, 0.11) | -9.03 (-24.2, 6.10) | -0.02 (-0.10, 0.07) | -0.02 (-0.10, 0.06) | -0.02 (-0.10, 0.07) | -0.02 (-0.1, 0.05) | -0.02 (-0.1, 0.07) | -0.02 (-0.10, 0.05) | -0.05 (-0.14, 0.03) | 0.04 (-0.01, 0.08) | 0.04 (-0.01, 0.09) | -0.06 (-0.14, 0.03) |
| Macronutrients | ||||||||||||||
| Plant protein | 0 (-0.15, 0.15) | 0 (-0.11, 0.11) | -0.01 (-0.09, 0.08) | 5.9 (-9.3, 21.0) | -0.03 (-0.12, 0.05) | -0.01 (-0.09, 0.07) | -0.03 (-0.12, 0.05) | -0.02 (-0.1, 0.05) | -0.03 (-0.12, 0.05) | -0.02 (-0.1, 0.05) | -0.04 (-0.12, 0.05) | -0.02 (-0.07, 0.03) | -0.02 (-0.07, 0.03) | -0.04 (-0.13, 0.05) |
| Animal protein | 0.06 (-0.09, 0.21) | 0.04 (-0.08, 0.15) | 0.01 (-0.08, 0.10) | -10.8 (-26.1, 4.50) | -0.02 (-0.11, 0.07) | 0.04 (-0.04, 0.12) | -0.02 (-0.11, 0.06) | 0.04 (-0.04, 0.12) | -0.02 (-0.11, 0.06) | 0.04 (-0.04, 0.12) | -0.03 (-0.12, 0.06) | 0 (-0.05, 0.05) | 0 (-0.05, 0.05) | -0.03 (-0.12, 0.06) |
| Plant fat | 0.01 (-0.14, 0.17) | 0.01 (-0.11, 0.13) | 0.02 (-0.08, 0.11) | -10.8 (-26.3, 4.70) | -0.03 (-0.12, 0.06) | 0.02 (-0.07, 0.1) | -0.03 (-0.12, 0.06) | 0.01 (-0.07, 0.09) | -0.03 (-0.12, 0.06) | 0.01 (-0.07, 0.09) | 0 (-0.09, 0.09) | -0.03 (-0.08, 0.02) | -0.03 (-0.08, 0.03) | 0 (-0.09, 0.09) |
| Animal fat | 0.07 (-0.08, 0.21) | 0.05 (-0.06, 0.17) | 0.03 (-0.06, 0.12) | -10.65 (-25.8, 4.50) | -0.01 (-0.1, 0.08) | 0.03 (-0.05, 0.11) | -0.01 (-0.1, 0.08) | 0.03 (-0.05, 0.11) | -0.01 (-0.1, 0.08) | 0.03 (-0.05, 0.11) | 0 (-0.09, 0.09) | -0.02 (-0.07, 0.03) | -0.02 (-0.07, 0.03) | 0 (-0.09, 0.09) |
| Carbohydrates | -0.11 (-0.26, 0.04) | -0.06 (-0.17, 0.06) | -0.02 (-0.11, 0.07) | 10.7 (-4.54, 25.9) | 0.02 (-0.07, 0.1) | -0.01 (-0.1, 0.07) | 0.02 (-0.07, 0.1) | -0.01 (-0.09, 0.07) | 0.02 (-0.07, 0.1) | -0.01 (-0.09, 0.07) | 0.01 (-0.07, 0.10) | -0.02 (-0.07, 0.03) | -0.02 (-0.07, 0.03) | 0.01 (-0.08, 0.10) |
| Fiber | 0 (-0.15, 0.15) | -0.02 (-0.13, 0.1) | -0.02 (-0.11, 0.07) | 1.3 (-14.2, 16.8) | -0.05 (-0.14, 0.03) | 0.05 (-0.04, 0.13) | -0.05 (-0.14, 0.03) | 0.03 (-0.05, 0.11) | -0.05 (-0.14, 0.03) | 0.03 (-0.04, 0.11) | -0.01 (-0.1, 0.08) | -0.02 (-0.07, 0.03) | -0.02 (-0.07, 0.03) | -0.01 (-0.10, 0.08) |
| Fatty acids | ||||||||||||||
| SFAs | -0.01 (-0.15, 0.14) | -0.04 (-0.15, 0.07) | -0.05 (-0.13, 0.04) | -10.0 (-24.8, 4.70) | 0.04 (-0.05, 0.12) | -0.01 (-0.09, 0.07) | 0.04 (-0.05, 0.12) | 0 (-0.08, 0.08) | 0.04 (-0.05, 0.12) | 0 (-0.07, 0.08) | 0.02 (-0.06, 0.10) | -0.02 (-0.07, 0.03) | -0.02 (-0.07, 0.03) | 0.02 (-0.07, 0.11) |
| MUFAs | -0.03 (-0.19, 0.12) | -0.05 (-0.17, 0.06) | -0.05 (-0.14, 0.04) | -9.6 (-25.0, 5.90) | 0 (-0.08, 0.09) | 0.01 (-0.07, 0.1) | 0 (-0.08, 0.09) | 0.02 (-0.06, 0.1) | 0 (-0.08, 0.09) | 0.02 (-0.06, 0.10) | 0.02 (-0.06, 0.11) | -0.01 (-0.06, 0.04) | -0.01 (-0.06, 0.04) | 0.03 (-0.06, 0.12) |
| PUFAs | 0.10 (-0.05, 0.26) | 0.05 (-0.07, 0.17) | 0.01 (-0.08, 0.11) | -13.6 (-29.4, 2.30) | -0.02 (-0.11, 0.07) | 0.05 (-0.03, 0.14) | -0.02 (-0.11, 0.07) | 0.06 (-0.02, 0.14) | -0.02 (-0.11, 0.07) | 0.06 (-0.02, 0.14) | -0.08 (-0.17, 0.01) | -0.01 (-0.06, 0.04) | -0.01 (-0.06, 0.04) | -0.08 (-0.17, 0.01) |
F/B Firmicutes/Bacteroidetes, SFAs saturated fatty acids, MUFAs monounsaturated fatty acids, PUFAs polyunsaturated fatty acids
aAlpha-diversity indices are log-transformed
bAdjusted for age, sex, family history of colorectal cancer, smoking status, alcohol consumption, body mass index, American Joint Committee on Cancer stage, neoadjuvant therapy, and comorbidity