Table 1.

miRNAs regulate the expression of YAP/TAZ and cancer progression

MiRNAs	Cancer type	Role in cancer	Targets	Functions	Reference
miR-599	bladder urothelial carcinoma	tumor suppressor	YAP1	inhibit proliferation, invasion, promote apoptosis	[46]
miR-15a-5p	cervical cancer	tumor suppressor	YAP1	inhibit viability, migration and invasion, induce apoptosis	[47]
miR-591	breast cancer	tumor suppressor	YAP1	inhibit proliferation and invasion	[48]
miR-1285-3p	osteosarcoma	tumor suppressor	YAP1	inhibit proliferation and invasion	[49]
miR-345	non-small cell lung cancer	tumor suppressor	YAP1	inhibit migration and invasion	[50]
miR-424-3p	non-small cell lung cancer	tumor suppressor	YAP1	inhibit proliferation,migration and invasion,enhance chemoresistance	[51]
miR-27a-3p	oral squamous cell carcinoma	tumor suppressor	YAP1	inhibit EMT process	[52]
miR-26b	non-small cell lung cancer	tumor suppressor	TAZ	suppress the cisplatin resistance	[53]
miR-92a-3p	cervical cancer	oncogene	LAST1	promote proliferation,invasion and cell cycle transition	[54]
miR-92	ovarian cancer	oncogene	LATS2	promote proliferation and migration, induce immune suppression	[55]
miRNA-224-3p	retinoblastoma	oncogene	LATS2	promote proliferation and angiogenesis,inhibit apoposis	[56]
miR-31	esophageal squamous cell carcinoma	oncogene	LATS2	promote proliferation, migration, invasion and EMT process, induce apoptosis	[57]
miR-520b	breast cancer	oncogene	LATS2	promote migration, EMT process and cancer cell stemness	[58]
miR-216a-3p	cervical cancer	tumor suppressor	ACTL6A	inhibit proliferation,migration	[59]