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. 2022 Jun 15;10:87. doi: 10.1186/s40478-022-01391-y

Table 2.

Correlations of the lateral geniculate (LGN) subregion with OCT and neuroperformance measures in relapsing MS

Correlation with lateral geniculate volume n Spearman rho coefficient P Median days IQR days
Baseline OCT measures
Average Ganglion Cell-Inner Plexiform (GC/IPL) 62 0.64  < 0.0001 29.0 165.5
Peripapillary RNFL 67 0.66  < 0.0001 29.0 170.5
Macular RNFL 31 0.55 0.001 21.0 83.0
Macular volume 63 0.54  < 0.0001 29.0 152.0
Outer retinal average thickness (macular scan) 31 0.03 0.85 21.0 83.0
Baseline Neuroperformance measures
Patient determined disease steps 747  − 0.22  < 0.0001 7.0 36.0
Dominant hand manual dexterity test 662  − 0.27  < 0.0001 5.0 33.0
Nondominant hand manual dexterity test 662  − 0.28  < 0.0001 5.0 33.0
Walking speed test 651  − 0.24  < 0.0001 5.0 33.0