Table 2B.

Proposed anatomical white matter substrate for glutamate-mediated within- and between-network connectivity.

Connectivity	DMN	AN	RN	CEN	SN	SMN	CAN
DMN	• Cortico-cortical • Hippocampal-cingulate	• Cortico-cortical • Hippocampal-cingulate • Amygdalo-cingulate	• Cortico-cortical • Cortico-striatal • Hippocampal-striatal-tegmental	• Cortico-cortical	• Cortico-cortical • Hippocampal-cingulate	• Cortico-cortical • Cortico-striatal • Cortico-brainstem • Cortico-thalamic • Thalamo-cortical • Hippocampal-striatal-tegmental	• Cortico-brainstem • Cortico-thalamic • Thalamo-cortical • Hippocampal-hypothalamic • Amygdalo-cingulate
AN	• Cortico-cortical • Hippocampal-cingulate • Amygdalo-cingulate	• Cortico-cortical • Hippocampal-cingulate • Amygdalo-cingulate	• Cortico-cortical • Cortico-striatal • Hippocampal-striatal-tegmental • Amygdalo-striatal	• Cortico-cortical	• Cortico-cortical • Hippocampal-cingulate • Amygdalo-cingulate	• Cortico-cortical • Cortico-striatal • Cortico-brainstem • Cortico-thalamic • Thalamo-cortical • Hippocampal-striatal-tegmental • Amygdalo-striatal	• Cortico-brainstem • Cortico-thalamic • Thalamo-cortical • Hippocampal-hypothalamic • Amygdalo-hypothalamic
RN	• Cortico-cortical • Cortico-striatal • Hippocampal-striatal-tegmental	• Cortico-cortical • Cortico-striatal • Hippocampal-striatal-tegmental • Amygdalo-striatal	• Cortico-striatal	• Cortico-cortical • Cortico-striatal	• Cortico-cortical • Cortico-striatal	• Cortico-cortical • Cortico-striatal • Cortico-brainstem • Cortico-thalamic • Thalamo-cortical	• Cortico-brainstem • Cortico-thalamic • Thalamo-cortical • Amygdalo-striatal
CEN	• Cortico-cortical	• Cortico-cortical	• Cortico-cortical • Cortico-striatal	• Cortico-cortical	• Cortico-cortical	• Cortico-cortical • Cortico-striatal • Cortico-brainstem • Cortico-thalamic • Thalamo-cortical	• Cortico-brainstem • Cortico-thalamic • Thalamo-cortical
SN	• Cortico-cortical • Hippocampal-cingulate	• Cortico-cortical • Hippocampal-cingulate • Amygdalo-cingulate	• Cortico-cortical • Cortico-striatal	• Cortico-cortical	• Cortico-cortical	• Cortico-cortical • Cortico-striatal • Cortico-brainstem • Cortico-thalamic • Thalamo-cortical	• Cortico-brainstem • Cortico-thalamic • Thalamo-cortical
SMN	• Cortico-cortical • Cortico-striatal • Cortico-brainstem • Cortico-thalamic • Thalamo-cortical • Hippocampal-striatal-tegmental	• Cortico-cortical • Cortico-striatal • Cortico-brainstem • Cortico-thalamic • Thalamo-cortical • Hippocampal-striatal-tegmental • Amygdalo-striatal	• Cortico-cortical • Cortico-striatal • Cortico-brainstem • Cortico-thalamic • Thalamo-cortical	• Cortico-cortical • Cortico-striatal • Cortico-brainstem • Cortico-thalamic • Thalamo-cortical	• Cortico-cortical • Cortico-striatal • Cortico-brainstem • Cortico-thalamic • Thalamo-cortical	• Cortico-cortical • Cortico-striatal • Cortico-brainstem • Cotrico-thalamic • Thalamo-cortical	• Cortico-brainstem • Cortico-thalamic • Thalamo-cortical • Amygdalo-striatal • Amygdalo-cingulate
CAN	• Cortico-brainstem • Cortico-thalamic • Thalamo-cortical • Hippocampal-hypothalamic • Amygdalo-cingulate	• Cortico-brainstem • Cortico-thalamic • Thalamo-cortical • Hippocampal-hypothalamic • Amygdalo-hypothalamic	• Cortico-brainstem • Cortico-thalamic • Thalamo-cortical • Amygdalo-striatal	• Cortico-brainstem • Cortico-thalamic • Thalamo-cortical	• Cortico-brainstem • Cortico-thalamic • Thalamo-cortical • Amygdalo-cingulate	• Cortico-brainstem • Cortico-thalamic • Thalamo-cortical • Amygdalo-striatal	• Cortico-brainstem • Cortico-thalamic • Thalamo-cortical • Hippocampal-hypothalamic • Amygdalo-hypothalamic

Intrinsic Connectivity Networks: AN, ventromedial affective network; CAN, frontovagal central autonomic network; CEN, frontoparietal central executive network; DMN, default mode network; RN, ventral frontostriatal reward network; SMN, frontocerebellar sensorimotor network; SN, anterior cinguloinsular salience network. Within-network connectivity pathways are italicized.