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. 2022 Jun 1;13:877807. doi: 10.3389/fendo.2022.877807

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Copyright © 2022 Wang, Mu, Zhang, Long, Zhang, Li, Zhao and Qiao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Developing a diagnostic signature of PCOS based on the metabolites in tryptophan-kynurenine pathway. (A) Diagnostic potential of TRP, tryptophan; KYN, kynurenine; KYNA,kynurenic acid and the endocrine indicators by ROC analysis to distinguish PCOS from control in all participants. (B) Diagnostic potential of the combination of TRP, tryptophan; KYN, kynurenine; KYNA,kynurenic acid with or without the endocrine indicators by ROC analysis to distinguish PCOS from control in all participants. T, total testosterone; AND, androstenedione.