Table 1.
Patient demographic and preoperative characteristics.
| Variable | Alemtuzumab | Basiliximab | p value | Odds Ratio | 95% CI |
|---|---|---|---|---|---|
| n = 453 | n = 354 | ||||
| Age, Median (IQR) | 60.23 (50.08 - 66.49) | 60.16 (50.03 - 66.02) | 0.58 | - | - |
| Age 70 or older | 39 (8.9) | 37 (10.7) | 0.42 | 1.22 | 0.76-1.95 |
| Sex | |||||
| Female | 201 (44.4) | 144 (40.7) | 0.29 | 1.16 | 0.88-1.54 |
| Male | 252 (55.6) | 210 (59.3) | |||
| Diagnosis | |||||
| COPD/Emphysema/BO | 153 (33.8) | 102 (28.8) | 0.002 | - | - |
| Pulmonary Fibrosis | 162 (35.8)* | 152 (42.9)* | |||
| Suppurative | 57 (12.6) | 59 (16.7) | |||
| Scleroderma | 54 (11.9)* | 19 (5.4)* | |||
| Pulmonary Hypertension | 9 (2.0) | 10 (2.8) | |||
| Occupational | 15 (3.3) | 6 (1.7) | |||
| Other | 3 (0.7) | 6 (1.7) | |||
| Lung allocation score, Median (IQR) | 43.6 (34.6 - 66.6) | 46.8 (36.1-67.9) | 0.07 | - | - |
| Body mass index, Median (IQR) | 25.6 (21.4 - 29.3) | 24.6 (20.9-28.7) | 0.07 | - | - |
| Waiting list time (days), Median (IQR) | 50.0 (16.0 - 143.0) | 46.5 (19.0-180.3) | 0.29 | - | - |
| Recipient CMV positive | 267 (58.9) | 104 (29.4) | < 0.001 | 0.29 | 0.22-0.39 |
| Recipient EBV positive | 436 (97.5) | 334 (95.7) | 0.15 | 0.56 | 0.26-1.24 |
| HCV history | 6 (1.3) | 18 (5.1) | 0.002 | 3.99 | 1.57-10.16 |
| HIV history | 0 (0.0) | 6 (1.7) | 0.005 | 0.43 | 0.40-0.47 |
| CMV Mismatch | 43 (9.5) | 213 (60.2) | < 0.001 | 14.4 | 9.86-21.05 |
| EBV Mismatch | 10 (2.2) | 14 (4.0) | 0.15 | 1.82 | 0.80-4.16 |
| Preoperative steroids | 195 (43.0) | 152 (42.9) | 0.98 | 1 | 0.75-1.32 |
| Preoperative hepatic disease | 9 (2.0) | 20 (5.6) | 0.006 | 2.94 | 1.32-6.54 |
| Oncology history | 13 (2.9) | 82 (23.2) | < 0.001 | 10.2 | 5.58-18.67 |
| ECMO Bridge | 36 (8.0) | 34 (9.6) | 0.41 | 1.23 | 0.75-2.01 |
*p < 0.05 post hoc. IQR, Interquartile range; COPD, Chronic obstructive pulmonary disease; BO, Bronchiolitis obliterans.