Skip to main content
. 2022 Jun 1;13:864545. doi: 10.3389/fimmu.2022.864545

Table 1.

Patient demographic and preoperative characteristics.

Variable Alemtuzumab Basiliximab p value Odds Ratio 95% CI
  n = 453 n = 354      
Age, Median (IQR) 60.23 (50.08 - 66.49) 60.16 (50.03 - 66.02) 0.58 - -
Age 70 or older 39 (8.9) 37 (10.7) 0.42 1.22 0.76-1.95
Sex          
 Female 201 (44.4) 144 (40.7) 0.29 1.16 0.88-1.54
 Male 252 (55.6) 210 (59.3)      
Diagnosis          
 COPD/Emphysema/BO 153 (33.8) 102 (28.8) 0.002 - -
 Pulmonary Fibrosis 162 (35.8)* 152 (42.9)*      
 Suppurative 57 (12.6) 59 (16.7)      
 Scleroderma 54 (11.9)* 19 (5.4)*      
 Pulmonary Hypertension 9 (2.0) 10 (2.8)      
 Occupational 15 (3.3) 6 (1.7)      
 Other 3 (0.7) 6 (1.7)      
Lung allocation score, Median (IQR) 43.6 (34.6 - 66.6) 46.8 (36.1-67.9) 0.07 - -
Body mass index, Median (IQR) 25.6 (21.4 - 29.3) 24.6 (20.9-28.7) 0.07 - -
Waiting list time (days), Median (IQR) 50.0 (16.0 - 143.0) 46.5 (19.0-180.3) 0.29 - -
Recipient CMV positive 267 (58.9) 104 (29.4) < 0.001 0.29 0.22-0.39
Recipient EBV positive 436 (97.5) 334 (95.7) 0.15 0.56 0.26-1.24
HCV history 6 (1.3) 18 (5.1) 0.002 3.99 1.57-10.16
HIV history 0 (0.0) 6 (1.7) 0.005 0.43 0.40-0.47
CMV Mismatch 43 (9.5) 213 (60.2) < 0.001 14.4 9.86-21.05
EBV Mismatch 10 (2.2) 14 (4.0) 0.15 1.82 0.80-4.16
Preoperative steroids 195 (43.0) 152 (42.9) 0.98 1 0.75-1.32
Preoperative hepatic disease 9 (2.0) 20 (5.6) 0.006 2.94 1.32-6.54
Oncology history 13 (2.9) 82 (23.2) < 0.001 10.2 5.58-18.67
ECMO Bridge 36 (8.0) 34 (9.6) 0.41 1.23 0.75-2.01

*p < 0.05 post hoc. IQR, Interquartile range; COPD, Chronic obstructive pulmonary disease; BO, Bronchiolitis obliterans.