Table 2:

Anxiety and depression and quality-of-life questionnaire scores

	N	Score	Change from baseline	p*	Patients with a score ≥8	Patients with ≥3 point change	Patients ≥3 point decrease	Patients with ≥3 point increase
Hospital Anxiety and Depression Scale-Anxiety†
Baseline	44	3 (1 to 5)	··	··	7 (16%)	··	··	··
Month 6	32	2 (1 to 5)	0 (−2 to −1)	0.53	5 (16%)	··	··	··
Month 12	22	3 (1 to 6)	0.5 (−2 to −1)	0.86	4 (18%)	··	··	··
Final assessment	29	3 (1 to 5)	−1 (−2 to −1)	0.14	3 (10%)	··	··	··
Hospital Anxiety and Depression Scale-Depression†
Baseline	44	1 (1 to 5)	··	··	2 (5%)	··	··	··
Month 6	32	1 (0 to 3)	0 (−2 to −1)	0.11	1 (3%)	··	··	··
Month 12	22	2 (1 to 4)	0 (−2 to 1)	0.52	2 (9%)	··	··	··
Final assessment	29	2 (1 to 3)	0 (−2 to 1)	0.87	2 (7%)	··	··	··
Functional Assessment of Cancer Therapy-Kidney Cancer Index Disease-Related Symptoms‡
Baseline	44	3 (0 to 14)	··	··	··	··	··	··
Month 6	32	3 (0 to 16)	O (−8 to 4)	0.76	··	10 (31%)	6 (19%)	4 (13%)
Month 12	22	3 (0 to 13)	O (−5 to 1O)	0.52	··	10 (45%)	4 (18%)	6 (27%)
Last assessment	28	4 (0 to 22)	1 (−7 to 16)	0.46	··	16 (57%)	8(29%)	8 (29%)

Data are median (IQR) or n (%), unless otherwise stated.

^*Wilcoxon signed-rank test.

^†Scores ≥8 on a subscale are suggestive of the presence of anxiety or depression.

^‡A change of ≥3 points is considered significant.¹³