Fig. 4.

Withania somnifera lead phytochemical docking pose and interaction with human host TMPRSS2 protein. A Docking pose of standard inhibitor and lead phytochemicals at TMPRSS2 protein active site. B Surface structure of TMPRSS2 protein with lead compound rutin. C Surface structure of TMPRSS2 protein with lead compound Isochlorogenic acid B. D Surface structure of TMPRSS2 interacted with standard inhibitor camostst mesylate. Green and orange color represents the amino acid involved in hydrogen bonding and hydrophobic interaction respectively