Fig. 6.

Binding energy of W. somnifera lead phytochemical groups against the targeted SARS-CoV-2 (Spike-glycoprotein and RdRp) and Human host (CD26 and TMPRSS2) test proteins. The lead (more potent binding in comparison to standard inhibitors of the targeted proteins) phytochemicals were groped as A’-Other phytochemicals; B’-Flavonoids/Polyphenoilcs; C’-Saponin; D’-Alkaloids; E’-Steroidal/Benzenoid lactones. Other phytochemicals included pentose phosphate, glucinolates, amino acids, fatty acids and cyclitol. The analysis was done on GraphPad Prism software using data provided in Table 1