Table 1.
Optimal CRP cut-offs to distinguish between patients with and without major infectious complications. Next to the optimal cut-offs, cut-offs for safe discharge are provided.
| Optimal cut-off | Cut-off | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | LR + | LR- |
|---|---|---|---|---|---|---|---|
| Postoperative day 3 | 175 | 80.0 | 69.7 | 40.% | 93.2 | 2.64 | 0.29 |
| Postoperative day 4 | 130 | 82.1 | 66.9 | 41.0 | 93.0 | 2.48 | 0.12 |
| Postoperative day 5 | 114 | 80.6 | 70.5 | 45.8 | 92.2 | 2.73 | 0.28 |
| Safe discharge criterion | |||||||
| Postoperative day 3 | 105 | 95.7 | 39.1 | 28.6 | 97.3 | 1.57 | 0.11 |
| Postoperative day 4 | 71 | 95.5 | 38.1 | 30.1 | 97.8 | 1.54 | 0.02 |
| Postoperative day 5 | 63 | 94.0 | 50.2 | 33.2 | 97.7 | 1.61 | 0.08 |
NPV indicates negative predictive value; PPV, positive predictive value; LR, likelihood ratio