TABLE 1.
First Author | Country | Journal | Study Population | Gender | Age | rTLT assay |
Num. | Obesity/ overweight |
Adjusted confounders | Main finding |
Linghui (37) | China | Fron Aging Neurosci | Healthy | Both | 65–80 | qPCR | 2,006 | Obesity | Unadjusted | Non-significant lower BMI in the highest vs. the lowest rTLT categories (P = 0.585) |
Zgheib (38) | Lebanon | Aging and Disease | Healthy | Both | > 18 | qPCR | 497 | Central obesity |
Unadjusted | BMI in the highest tertile of rLTL was significantly lower than the lowest (P = 0.045) |
Milte (39) | Australia | Eur J Nutr | Healthy | Both | 57–68 | qPCR | 679 | Obesity | Unadjusted | Non-significant lower BMI in the highest vs. the lowest rTLT categories (P = 0.116) |
Mazidi (40) | United States | Angiology | Healthy | Both | > 18 | qPCR | 8,892 | Obesity | Age, race, sex |
Non-significant lower BMI in the highest vs. the lowest rTLT categories (P = 0.312) |
Mwasongwe (41) | United States | Atherosclerosis | Healthy | Both | > 21 | qPCR | 5,306 | Obesity | Age, sex | Non-significant higher BMI in the highest vs. the lowest rTLT categories (P = 0.30) |
Mazidi (42) | United States | Oncotarget | Healthy | Both | > 18 | qPCR | 5,020 | Obesity | Unadjusted | BMI in the highest rLTL quartile (26.4 ± 0.21) was significantly lower than the lowest (28.5 ± 0.18) P < 0.001 |
Julin (43) | United States | Eur J Nutr | Healthy | Men | 40–75 | qPCR | 2,483 | Obesity | Age | BMI in the highest rLTL quartile (25.8 ± 3.2) was significantly lower than the lowest (26.2 ± 3.5) P = 0.05 |
Hardikar (44) | United States | BMC Obesity | Barrett’s esophagus | Both | 50–70 | qPCR | 295 | Obesity | Age, sex | BMI in the highest rLTL quartile (29.1 ± 4.3) was significantly higher than the lowest (28.1 ± 3.6) P = 0.05 |
Zalli (45) | United Kingdom | PNAS | Healthy | Both | 54–76 | qPCR | 333 | Obesity | Unadjusted | No significant difference between the lowest vs. the highest rTLT categories |
Chen (5) | United States | Aging | Healthy | Both | 30–50 | qPCR | 3,256 | Obesity | Age | BMI in the highest rLTL quartile (30.1 ± 7.6) was significantly lower than the lowest (33 ± 7.6) P < 0.001 |
Liu (46) | United States | Am J Epidemilo | Healthy | Both | 30–55 | qPCR | 4,604 | Obesity | Age | BMI in the highest rLTL quartile (25.4.1 ± 4.5) was significantly lower than the lowest (25.8 ± 5) P = 0.03 |
Cassidy (4) | United States | Am J Clin Nutr | Healthy | Women | 30–55 | qPCR | 2,284 | Obesity | Age | BMI in the highest rLTL quartile (25.3.1 ± 4.3) was significantly lower than the lowest (26 ± 4.9) P = 0.005 |