TABLE 1.

Prevalence, overall frequency, and mechanism of potential DDIs relating to contraindication or warned against concomitant uses identified among emergency admissions (n = 5860)

	n (%)	Overall frequency, % (95% CI)	Pharmacodynamic, n (%)	Pharmacokinetic, n (%)
Overall	375	6.4 (5.8, 7.0)	326 (86.9)	49 (13.1)
Contraindicated a	163 (43.5)	2.8 (2.4, 3.2)	151 (92.6)	12 (7.4)
Warned against b	212 (56.5)	3.6 (3.1, 4.1)	175 (82.5)	37 (17.5)

Abbreviations: 95% CI, 95% confidence interval; DDIs, drug‐drug interactions.

^a Contraindicated concomitant uses.

^b Warned against concomitant uses.